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脑卒中幸存者上肢运动功能恢复的预测因素:前后测试设计研究。

Predictors of upper limb motor recovery in stroke survivors: a pre-post test study design.

机构信息

Department of Physiotherapy, University of Zambia, Lusaka, Zambia

Department of Epidemiology and Biostatistics, University of Zambia School of Public Health, Lusaka, Zambia.

出版信息

BMJ Open. 2024 Nov 28;14(11):e081936. doi: 10.1136/bmjopen-2023-081936.

DOI:10.1136/bmjopen-2023-081936
PMID:39613425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11605842/
Abstract

OBJECTIVES

The study aimed to assess the predictors of upper limb motor recovery in stroke survivors.

DESIGN

Pre-post test study design.

SETTING

Conducted in two centres (First Level Hospital and University Teaching Hospital in Lusaka).

PARTICIPANTS

Patients living with stroke accessing physiotherapy services at the two public hospitals. A total of 52 patients were recruited at the start of the study, 6 were lost to follow-up and 46 completed the study.

INTERVENTION

Conventional physiotherapy for 8 weeks (5 September 2022-28 October 2022).

PRIMARY OUTCOME

Motor function measured using a Fugl-Meyer assessment of the upper extremity.

RESULTS

Analysis was conducted on 46 participants. A significant difference was observed between the level of motor function at baseline and after 8 weeks of treatment (p=0.0183). At baseline, 50% of participants had mild motor function, which improved after 8 weeks, with 69.6% having mild motor function. Stroke patients with severe motor function impairment at baseline were associated with 0.01 times likelihood of having mild motor function impairment after 8 weeks of physiotherapy treatment (AOR 0.01; 95 % CI 0.00 to 0.16; p=0.002).

CONCLUSION

The motor function of stroke patients continues to improve over time. This study demonstrated that initial upper limb motor function impairment could be used as a predictor for upper limb motor function.

摘要

目的

本研究旨在评估脑卒中幸存者上肢运动功能恢复的预测因素。

设计

前后测试研究设计。

地点

在两个中心(卢萨卡的一级医院和大学教学医院)进行。

参与者

在这两家公立医院接受物理治疗服务的脑卒中患者。在研究开始时共招募了 52 名患者,有 6 名患者失访,46 名患者完成了研究。

干预措施

常规物理治疗 8 周(2022 年 9 月 5 日至 10 月 28 日)。

主要结局

上肢运动功能采用 Fugl-Meyer 上肢评估进行测量。

结果

对 46 名参与者进行了分析。在基线和治疗 8 周后,运动功能水平之间观察到显著差异(p=0.0183)。基线时,50%的参与者上肢运动功能轻度受损,经过 8 周治疗后,69.6%的患者上肢运动功能轻度受损。基线时上肢运动功能严重受损的脑卒中患者在接受 8 周物理治疗后上肢运动功能轻度受损的可能性降低 0.01 倍(AOR 0.01;95%CI 0.00 至 0.16;p=0.002)。

结论

脑卒中患者的运动功能随时间推移持续改善。本研究表明,初始上肢运动功能损伤可作为上肢运动功能的预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2581/11605842/f35e8d875f3a/bmjopen-14-11-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2581/11605842/5aaf3fac9dff/bmjopen-14-11-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2581/11605842/f35e8d875f3a/bmjopen-14-11-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2581/11605842/5aaf3fac9dff/bmjopen-14-11-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2581/11605842/f35e8d875f3a/bmjopen-14-11-g002.jpg

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本文引用的文献

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Life (Basel). 2023 Oct 15;13(10):2061. doi: 10.3390/life13102061.
2
Update on Stroke Rehabilitation in Motor Impairment.运动功能障碍的中风康复新进展
Brain Neurorehabil. 2022 Jul 20;15(2):e12. doi: 10.12786/bn.2022.15.e12. eCollection 2022 Jul.
3
Predictors for Upper-Limb Functional Recovery Trajectory in Individuals Receiving Stroke Rehabilitation: A Secondary Analysis of Data from Randomized Controlled Trials.
接受脑卒中康复治疗的个体上肢功能恢复轨迹的预测因素:来自随机对照试验数据的二次分析。
Int J Environ Res Public Health. 2022 Dec 8;19(24):16514. doi: 10.3390/ijerph192416514.
4
Early prediction of upper limb functioning after stroke using clinical bedside assessments: a prospective longitudinal study.使用临床床边评估对卒中后上肢功能进行早期预测:一项前瞻性纵向研究。
Sci Rep. 2022 Dec 21;12(1):22053. doi: 10.1038/s41598-022-26585-1.
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Multimodal Imaging Biomarker-Based Model Using Stratification Strategies for Predicting Upper Extremity Motor Recovery in Severe Stroke Patients.基于多模态影像生物标志物的分层策略预测重症脑卒中患者上肢运动功能恢复的模型
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