Spurr Shelley, Bally Jill, Allan Diane, Bullin Carol, McNair Erick
Faculty of Nursing, College of Nursing University of Saskatchewan Saskatoon Saskatchewan Canada.
Faculty of Medicine, College of Medicine University of Saskatchewan Saskatoon Saskatchewan Canada.
Endocrinol Diabetes Metab. 2019 Mar 1;2(2):e00060. doi: 10.1002/edm2.60. eCollection 2019 Apr.
To identify the presence of risk factors for type 2 diabetes (ethnicity, body mass index, blood glucose tolerance and blood pressure) and to determine the prevalence of prediabetes and type 2 diabetes in Canadian adolescents attending two multicultural urban high schools.
A total of 266 multicultural urban high school students who live in a mid-sized Western Canadian city, aged 14-21, were screened for risk factors of prediabetes and type 2 diabetes in March-April 2018. Data with respect to demographics, family history of diabetes, anthropometrics, blood pressure and haemoglobin A1c (HbA1c) were collected. Data analysis was done using descriptive and inferential statistics in addition to chi-square analyses.
Based on body mass index, 38% of the adolescents were classified as either overweight or obese. Overweight rates for females (69.8%) were double than males (30.2%); however, males (52.2%) were more likely to obese than the females (47.8%). Based on HbA1c levels, 29.3% were at high risk to develop either diabetes or prediabetes and 2.6% were classified in the prediabetes range. Prehypertension/hypertension rates of 47% in the sample increased to 51% in those adolescents with elevated HbA1c; the majority of these prehypertensive/hypertensive participants were male.
High rates of overweight/obesity and prehypertension/hypertension were found in the adolescents studied and indicated the presence of prediabetes and an increased risk to develop type 2 diabetes and associated complications. Obesity and hypertension are major risk factors for developing type 2 diabetes, resulting in earlier exposure to metabolic consequences and, ultimately, long-term complications. Thus, timely research is needed to identify age-appropriate strategies that address risks and to develop recommendations for routine screening of adolescents for prediabetes.
确定2型糖尿病风险因素(种族、体重指数、血糖耐量和血压)的存在情况,并确定就读于两所多元文化城市高中的加拿大青少年中糖尿病前期和2型糖尿病的患病率。
2018年3月至4月,对居住在加拿大西部一个中等规模城市、年龄在14至21岁的266名多元文化城市高中生进行了糖尿病前期和2型糖尿病风险因素筛查。收集了有关人口统计学、糖尿病家族史、人体测量学、血压和糖化血红蛋白(HbA1c)的数据。除卡方分析外,还使用描述性和推断性统计进行数据分析。
根据体重指数,38%的青少年被归类为超重或肥胖。女性超重率(69.8%)是男性(30.2%)的两倍;然而,男性(52.2%)比女性(47.8%)更易肥胖。根据HbA1c水平,29.3%的人有患糖尿病或糖尿病前期的高风险,2.6%的人被归类为糖尿病前期范围。样本中47%的高血压前期/高血压率在HbA1c升高的青少年中升至51%;这些高血压前期/高血压参与者大多数为男性。
在研究的青少年中发现了高超重/肥胖率和高血压前期/高血压率,这表明存在糖尿病前期,以及患2型糖尿病和相关并发症的风险增加。肥胖和高血压是患2型糖尿病的主要风险因素,会导致更早暴露于代谢后果,最终引发长期并发症。因此,需要及时开展研究,以确定适合年龄的应对风险的策略,并制定针对青少年糖尿病前期进行常规筛查的建议。