At the University of Bielsko-Biala, Poland, Anna Pielesz, PhD, is Professor, Faculty of Materials, Civil and Environmental Engineering; Andrzej Gawłowski, PhD, is Professor, Faculty of Materials, Civil and Environmental Engineering; Dorota Biniaś, PhD, is Professor, Faculty of Materials, Civil and Environmental Engineering; Rafał Bobiński, PhD, is Dean, Faculty of Health Sciences; Marek Kawecki, Prof Dr, is Professor, Faculty of Health Sciences; Ewa Sama, PhD, is Professor, Faculty of Materials, Civil and Environmental Engineering; and Wioletta Waksmańska, PhD, is Vice Dean, Faculty of Health Sciences.
Adv Skin Wound Care. 2019 May;32(5):1-7. doi: 10.1097/01.ASW.0000554446.59743.9f.
To analyze specific spectroscopic (FT-Raman) and thermal (limiting oxygen index) aspects of skin samples exposed to electrical injury compared with thermal injury.
An observational case-control study was conducted at the Dr Stanislaw Sakiel Center for Burns Treatment in Siemianowice, Silesia, Poland. A scanning electron microscope was used to diagnose and illustrate the topography of skin samples from electrical and thermal burns and the morphologic effects on damaged versus undamaged skin surfaces. In particular, researchers attempted to detect spectroscopic and thermal changes at the molecular level, namely, specific biomarkers of tissue degeneration and their regeneration under the influence of the applied modifiers (antioxidants and orthosilicic acid solutions).
Modification with L-ascorbic acid and hydrogel of orthosilicic acid caused an increase in the intensity of the amide I Raman peaks, whereas modification with sodium ascorbate and orthosilicic acid resulted in the separation of the band protein side chains (1,440-1,448 cm), which is a part of tissue regeneration. The best result was obtained when the skin was treated with 7% orthosilicic acid (limiting oxygen index, 26%).
Antioxidant treatment may be advantageous in minimizing injury in patients with thermal burns but not always in electrical burns.
分析与热烧伤相比，暴露于电损伤的皮肤样本的特定光谱（FT-Raman）和热（极限氧指数）方面。
在波兰西里西亚西米亚诺维采的斯坦尼斯瓦夫·萨基尔烧伤治疗中心进行了一项观察性病例对照研究。使用扫描电子显微镜诊断和说明来自电烧伤和热烧伤的皮肤样本的形貌，并观察损伤和未损伤皮肤表面的形态效应。研究人员特别试图在分子水平上检测光谱和热变化，即组织退化的特定生物标志物及其在应用调节剂（抗氧化剂和正硅酸溶液）影响下的再生。
用 L-抗坏血酸和正硅酸水凝胶修饰会增加酰胺 I Raman 峰的强度，而用抗坏血酸钠和正硅酸修饰会导致蛋白质侧链（1,440-1,448 cm）分离，这是组织再生的一部分。当皮肤用 7%的正硅酸（极限氧指数为 26%）处理时，效果最佳。
抗氧化治疗可能有利于减轻热烧伤患者的损伤，但并非总是对电烧伤有效。
