Suppr超能文献

小儿卵巢肿瘤:儿科医生和妇科医生面临的挑战——三例病例报告(符合CARE标准)

Pediatric ovarian tumors, a challenge for pediatrician and gynecologist: Three case reports (CARE compliant).

作者信息

Mărginean Cristina Oana, Mărginean Claudiu, Chinceşan Mihaela, Mărginean Maria Oana, Meliţ Lorena Elena, Săsăran Vlăduţ, Mărginean Cristian Dan

机构信息

Department of Pediatrics I.

Department of Obstetrics and Gynecology.

出版信息

Medicine (Baltimore). 2019 Apr;98(16):e15242. doi: 10.1097/MD.0000000000015242.

Abstract

RATIONALE

Ovarian or adnexal tumors are very rare in patients below the age of 18 years, most of them being functional cysts, only 10% being malignant. We report 3 cases of ovarian tumors with the aim of revealing the particularities regarding the diagnosis and management of benign and malignant ovarian tumors in pediatric patients.

PATIENT CONCERNS

The 1st case, a 9-year-old girl presented for diffuse abdominal pain, distended abdomen and rapid increase in abdominal volume. The 2nd case describes a 13-year-old female patient admitted for acute abdominal pain and nausea, and the 3rd one was an 18-year-old female teenager who presented for distended abdomen, intermittent diffuse abdominal pain and rapid increase in abdomen volume.

DIAGNOSES

The abdominal ultrasound revealed in all 3 patients suggestive signs for ovarian tumors.

INTERVENTIONS

The 1st patient underwent laparotomy with adnexectomy, and the histopathological exam showed the diagnosis of dysgerminoma. The 2nd patient underwent laparoscopy with adnexectomy, and the histopathological exam revealed a borderline tumor. The 3rd patient benefited by a laparotomy with left ovariectomy, and the histopathological exam pointed out a mature teratoma.

OUTCOMES

The outcome was favorable in all 3 cases, but the patients with dysgerminoma and mature teratoma were further referred to the oncologist for proper assessment.

LESSONS

Laparoscopy may represent the first choice for uncomplicated ovarian masses. The diagnosis and the therapeutic plan must be based on symptoms, pelvic ultrasound, the time of menarche and the potential serum markers.

摘要

原理

卵巢或附件肿瘤在18岁以下患者中非常罕见,其中大多数为功能性囊肿,只有10%为恶性。我们报告3例卵巢肿瘤病例,旨在揭示小儿患者良性和恶性卵巢肿瘤诊断与管理的特殊性。

患者情况

第1例,一名9岁女孩因弥漫性腹痛、腹部膨隆及腹围迅速增加前来就诊。第2例描述的是一名13岁女性患者,因急性腹痛和恶心入院,第3例是一名18岁女性青少年,因腹部膨隆、间歇性弥漫性腹痛及腹围迅速增加前来就诊。

诊断

腹部超声在所有3例患者中均显示出提示卵巢肿瘤的征象。

干预措施

第1例患者接受了剖腹探查及附件切除术,组织病理学检查显示诊断为无性细胞瘤。第2例患者接受了腹腔镜下附件切除术,组织病理学检查显示为交界性肿瘤。第3例患者接受了剖腹探查及左侧卵巢切除术,组织病理学检查显示为成熟畸胎瘤。

结果

所有3例患者的预后均良好,但无性细胞瘤和成熟畸胎瘤患者被进一步转诊至肿瘤学家处进行适当评估。

经验教训

腹腔镜检查可能是单纯性卵巢肿块的首选。诊断和治疗方案必须基于症状、盆腔超声、初潮时间及潜在的血清标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b68d/6494269/594754e6318c/medi-98-e15242-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验