Department of Mechanical Engineering, Iowa State University of Science and Technology, 2529 Union Drive, Ames, IA, 50011, USA.
Department of Mechanical Engineering, Iowa State University of Science and Technology, 2529 Union Drive, Ames, IA, 50011, USA.
J Mech Behav Biomed Mater. 2019 Jul;95:180-190. doi: 10.1016/j.jmbbm.2019.04.005. Epub 2019 Apr 16.
The ongoing conflict against terrorism has resulted in an escalation of blast-induced traumatic brain injuries (bTBI) caused by improvised explosive devices (IEDs). The destructive IEDs create a blast wave that travels through the atmosphere. Blast-induced traumatic brain injuries, attributed to the blast wave, can cause life-threatening injuries and fatalities. This study aims to find a surrogate brain material for assessing the effectiveness of head protection systems designed to mitigate bTBI. Polydimethylsiloxane (PDMS) is considered as the surrogate brain material. The stiffness of PDMS (Sylgard 184, Dow Corning Corp.) can be controlled by varying the ratio of base and curing agent. Cylindrical PDMS specimen with ratios of 1:10, 1:70, and 1:80 were subjected to unconfined compression experiments at linear rates of 5 mm/min, 50 mm/min, and 500 mm/min. A ramp-hold strain profile was used to simulate a stress relaxation experiment. The fractional Zener viscoelastic model was used to describe the stress relaxation response, after optimization of the material constants for the brain surrogate and shock wave exposure brain tissue. The results show that the low cost PDMS can be used as a surrogate brain material to study the dynamic brain response to blast wave exposure.
针对恐怖主义的持续斗争导致简易爆炸装置 (IED) 引发的爆炸伤性脑损伤 (bTBI) 呈上升趋势。破坏性的 IED 会产生冲击波,在大气中传播。由冲击波引起的爆炸伤性脑损伤可能导致危及生命的伤害和死亡。本研究旨在寻找一种替代脑组织材料,用于评估旨在减轻 bTBI 的头部保护系统的有效性。聚二甲基硅氧烷 (PDMS) 被认为是替代脑组织材料。PDMS(道康宁公司的 Sylgard 184)的刚度可以通过改变基础料和固化剂的比例来控制。比例为 1:10、1:70 和 1:80 的圆柱形 PDMS 试样在 5mm/min、50mm/min 和 500mm/min 的线性速率下进行无约束压缩实验。使用斜坡保持应变曲线来模拟应力松弛实验。分数泽纳粘弹性模型用于描述脑组织冲击暴露后的应力松弛响应,对脑组织冲击暴露的脑代用品和材料常数进行了优化。结果表明,低成本 PDMS 可用作替代脑组织材料,用于研究大脑对冲击波暴露的动态响应。