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大脑多结节性和空泡性神经元肿瘤:一种罕见的神经影像学偶发病变,还是局灶性癫痫的潜在可治疗病因?

Multinodular and vacuolating neuronal tumour of the cerebrum: a rare neuroimaging incidentaloma or a potentially treatable cause of focal epilepsy?

机构信息

Institute for Neurosurgery.

Clinic of Neurology.

出版信息

Epileptic Disord. 2019 Apr 1;21(2):209-214. doi: 10.1684/epd.2019.1045.

Abstract

Multinodular and vacuolating neuronal tumour (MVNT) of the cerebrum is a relatively new, well defined histopathological and neuroradiological entity, in many cases associated with an early adult-onset epilepsy. These lesions have an indolent course and resemble both malformative and neoplastic processes, combining a focal developmental anomaly and a low-grade tumour. Herein, we report a case of a 48-year-old female patient with left temporal lobe epilepsy associated with MVNT. In addition, a comprehensive review of all the previously published cases is provided with a focus on seizure-related cases, surgical treatment, and postoperative outcome.

摘要

大脑多结节和空泡性神经元肿瘤 (MVNT) 是一种相对较新的、明确的组织病理学和神经影像学实体,在许多情况下与早发性成年期癫痫有关。这些病变具有惰性病程,类似于发育异常和肿瘤性病变,结合了局灶性发育异常和低度肿瘤。在此,我们报告了一例 48 岁女性患者,左侧颞叶癫痫伴 MVNT。此外,还对所有已发表的病例进行了全面回顾,重点关注与癫痫发作相关的病例、手术治疗和术后结果。

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