Burk D L, Brunberg J A, Kanal E, Latchaw R E, Wolf G L
Radiology. 1987 Mar;162(3):797-801. doi: 10.1148/radiology.162.3.3101136.
Twelve patients with neurofibromatosis affecting the spine and paraspinal regions were examined with magnetic resonance (MR) imaging performed using a 1.5-T magnet, surface coils, and spin-echo pulse sequences. In all 11 patients with neurofibromas, these tumors had slightly greater signal intensity than muscle on T1-weighted images and markedly increased signal intensity on T2-weighted images. In seven patients central areas of decreased signal intensity within the neurofibromas were demonstrated on T2-weighted images. In one patient these central areas corresponded pathologically to relatively fibrous components of the tumors surrounded by myxoid matrix. Five patients had extensive plexiform neurofibromatosis, one had lateral meningoceles, one had a neurofibrosarcoma, three had extradural spinal cord compression, and two had cystic intramedullary tumors of the spinal cord. The ability to obtain high-resolution, multiplanar images in a noninvasive fashion makes surface coil MR imaging an ideal technique for evaluating neurofibromatosis involving the spinal cord, spinal canal, and paraspinal soft tissues.
对12例患有累及脊柱和椎旁区域的神经纤维瘤病的患者进行了磁共振（MR）成像检查，使用1.5-T磁体、表面线圈和自旋回波脉冲序列。在所有11例患有神经纤维瘤的患者中，这些肿瘤在T1加权图像上的信号强度略高于肌肉，在T2加权图像上信号强度明显增加。在7例患者中，T2加权图像显示神经纤维瘤内信号强度降低的中央区域。在1例患者中，这些中央区域在病理上对应于被黏液样基质包围的肿瘤相对纤维性成分。5例患者患有广泛的丛状神经纤维瘤病，1例患有外侧脑脊膜膨出，1例患有神经纤维肉瘤，3例患有硬膜外脊髓压迫，2例患有脊髓囊性髓内肿瘤。以非侵入性方式获得高分辨率多平面图像的能力使表面线圈MR成像成为评估累及脊髓、椎管和椎旁软组织的神经纤维瘤病的理想技术。
