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多疗程立体定向体部放射治疗肾细胞癌后肾功能的长期控制与保留

Long term control and preservation of renal function after multiple courses of stereotactic body radiation therapy for renal cell carcinoma.

作者信息

Reddy Abhinav V, Mills Matthew N, Liauw Stanley L, Baliga Sujith, Kersh Charles R

机构信息

Transitional Year Program, Riverside Regional Medical Center, Newport News, Virginia, USA.

出版信息

Can J Urol. 2019 Apr;26(2):9743-9745.

PMID:31012841
Abstract

Renal cell carcinoma (RCC) is usually treated with surgery, with or without systemic therapy. For select patients, stereotactic body radiation therapy (SBRT) may be a suitable alternative. Although many reports exist on the successful use of SBRT, very few have described long term outcomes with regard to disease progression and renal function. We report a rare case of a single patient with primary, metastatic, and locally recurrent renal cell carcinoma who was successfully treated with SBRT. The patient has been disease-free for 8 years since treatment, with stable renal function even after two courses of SBRT to her solitary functioning kidney.

摘要

肾细胞癌(RCC)通常采用手术治疗,可联合或不联合全身治疗。对于部分患者,立体定向体部放射治疗(SBRT)可能是一种合适的替代治疗方法。虽然有许多关于成功使用SBRT的报道,但很少有描述疾病进展和肾功能方面的长期结果。我们报告了一例罕见病例,一名原发性、转移性和局部复发性肾细胞癌患者成功接受了SBRT治疗。自治疗以来,该患者已无病生存8年,即使在对其孤立的功能肾进行两疗程SBRT后,肾功能仍保持稳定。

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