Efira A, Cauchie P, Rauis M, de Maertelaere E
Acta Haematol. 1986;76(2-3):124-6. doi: 10.1159/000206035.
A platelet survival study with indium-111 oxine was performed in 6 patients with a myelodysplastic syndrome. A markedly shortened platelet life-span (range 0.50-2.65 days; normal 6.5-12 days) was obtained in each case. Platelet production ranged from 53,100 to 430,800 platelets/mm3/day (normal 66,200 +/- 14,600). A second isotopic study was performed in 1 case with platelets from a normal compatible donor. The nearly complete normalisation of the platelet life-span (from 0.85 to 5.50 days) indicates an intracorpuscular origin of the defect.
对6例骨髓增生异常综合征患者进行了铟-111草酸盐血小板存活研究。每例患者均出现血小板寿命显著缩短(范围为0.50 - 2.65天;正常为6.5 - 12天)。血小板生成量为53,100至430,800个血小板/mm³/天(正常为66,200 ± 14,600)。对1例患者使用来自正常匹配供体的血小板进行了第二项同位素研究。血小板寿命几乎完全恢复正常(从0.85天至5.50天),表明该缺陷源于细胞内。