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巨细胞病毒感染的一种不常见表现:全身性水肿。

An Unusual Presentation of Cytomegalovirus Infection: Generalized Edema.

机构信息

Department of Pediatric Gastroenterology, Hepatology and Nutrition, Turkish Republic Health Ministry, Ankara Child Health Diseases, Haematology Oncology Training and Research Hospital, Ankara, Turkey,

Department of Pediatric Gastroenterology, Hepatology and Nutrition, Turkish Republic Health Ministry, Ankara Child Health Diseases, Haematology Oncology Training and Research Hospital, Ankara, Turkey.

出版信息

Med Princ Pract. 2020;29(1):94-96. doi: 10.1159/000500511. Epub 2019 Apr 24.

Abstract

OBJECTIVE

Cytomegalovirus (CMV) infection may rarely lead to protein-losing gastropathy that presents with nausea, vomiting, abdominal pain, and edema in immunocompetent children, but extremely rarely with only generalized edema.

CLINICAL PRESENTATION AND INTERVENTION

A previously healthy 5-year-old boy presented with generalized edema without any other symptoms. He had hypoalbuminemia but no proteinuria. He was evaluated for gastrointestinal protein loss, and hypertrophic gastropathy was revealed on esophagogastroduodenoscopy. Meanwhile, CMV infection was detected by serologic tests and polymerase chain reaction in the blood. He recovered spontaneously within a week.

CONCLUSION

CMV-related protein-losing gastropathy may present with generalized edema without any gastrointestinal symptoms.

摘要

目的

巨细胞病毒(CMV)感染罕见情况下可能导致蛋白丢失性胃病,表现为免疫功能正常的儿童出现恶心、呕吐、腹痛和水肿,但极罕见情况下仅表现为全身性水肿。

临床特征及干预措施

一名既往健康的 5 岁男孩出现全身性水肿,无其他任何症状。他白蛋白水平降低,但无蛋白尿。对其进行胃肠道蛋白丢失评估,食管胃十二指肠镜检查显示为肥厚性胃病。同时,通过血清学检测和血液聚合酶链反应检测到 CMV 感染。他在一周内自行恢复。

结论

CMV 相关蛋白丢失性胃病可表现为无任何胃肠道症状的全身性水肿。

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