• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肾细胞癌伴下腔静脉肿瘤血栓患者对纳武单抗的强烈反应。

Robust response to nivolumab in patient with renal cell carcinoma inferior vena cava tumour thrombus.

作者信息

Berends Joel, Gourley Eric, Kaushik Dharam

机构信息

Department of Urology, University of Texas Health, San Antonio, Texas, USA.

出版信息

BMJ Case Rep. 2019 Apr 23;12(4):e227030. doi: 10.1136/bcr-2018-227030.

DOI:10.1136/bcr-2018-227030
PMID:31015235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6506063/
Abstract

A 47-year-old previously healthy man presented with acute moderate flank pain. Evaluation revealed left renal cell carcinoma, with inferior vena cava tumour thrombus invasion. Patient had no significant history or risk factors to pre-dispose him to genitourinary cancers. Surgery was deemed to not be appropriate due to distant metastases, but patient received targeted molecular therapy and immunotherapy with striking regression of the thrombus.

摘要

一名47岁既往健康的男性出现急性中度胁腹疼痛。检查发现左肾细胞癌,伴有下腔静脉肿瘤血栓侵犯。患者无明显病史或危险因素使其易患泌尿生殖系统癌症。由于远处转移,手术被认为不合适,但患者接受了靶向分子治疗和免疫治疗,血栓明显消退。

相似文献

1
Robust response to nivolumab in patient with renal cell carcinoma inferior vena cava tumour thrombus.肾细胞癌伴下腔静脉肿瘤血栓患者对纳武单抗的强烈反应。
BMJ Case Rep. 2019 Apr 23;12(4):e227030. doi: 10.1136/bcr-2018-227030.
2
Complete response of renal cell carcinoma vena cava tumor thrombus to neoadjuvant immunotherapy.肾细胞癌静脉癌栓完全缓解对新辅助免疫治疗的反应。
J Immunother Cancer. 2019 Mar 11;7(1):66. doi: 10.1186/s40425-019-0546-8.
3
Positron emission tomography imaging of renal vein and inferior vena cava tumor thrombus from renal cell carcinoma.肾细胞癌肾静脉及下腔静脉肿瘤血栓的正电子发射断层显像
Clin Nucl Med. 2005 Feb;30(2):107-9. doi: 10.1097/00003072-200502000-00009.
4
Surgical treatment of renal cell carcinoma: Can morphological features of inferior vena cava tumor thrombus on computed tomography or magnetic resonance imaging be a prognostic factor?肾细胞癌的外科治疗:计算机断层扫描或磁共振成像下腔静脉瘤栓的形态学特征能否作为预后因素?
Int J Urol. 2017 Feb;24(2):102-109. doi: 10.1111/iju.13272. Epub 2017 Jan 22.
5
The impact of targeted molecular therapies on the level of renal cell carcinoma vena caval tumor thrombus.靶向分子治疗对肾细胞癌下腔静脉瘤栓水平的影响。
Eur Urol. 2011 Jun;59(6):912-8. doi: 10.1016/j.eururo.2011.02.032. Epub 2011 Feb 23.
6
Renal Cell Carcinoma With Extensive Tumor Thrombus Into the Inferior Vena Cava and Right Atrium in a 70-Year-Old Man.70 岁男性,肾细胞癌伴下腔静脉及右心房广泛癌栓。
Am J Mens Health. 2019 May-Jun;13(3):1557988319846404. doi: 10.1177/1557988319846404.
7
Renal vein ostium wall invasion of renal cell carcinoma with an inferior vena cava tumor thrombus: prediction by renal and vena caval vein diameters and prognostic significance.伴有下腔静脉瘤栓的肾细胞癌肾静脉开口壁侵犯:通过肾静脉和腔静脉直径预测及预后意义
J Urol. 2008 Feb;179(2):450-4; discussion 454. doi: 10.1016/j.juro.2007.09.042.
8
Tumour thrombus consistency: a new tool to stage patients with pT3 renal cell carcinoma (RCC) with venous tumour thrombus?肿瘤血栓质地:一种对伴有静脉肿瘤血栓的pT3期肾细胞癌(RCC)患者进行分期的新工具?
BJU Int. 2014 Feb;113(2):182-3. doi: 10.1111/bju.12394.
9
Important surgical considerations in the management of renal cell carcinoma (RCC) with inferior vena cava (IVC) tumour thrombus.肾细胞癌(RCC)合并下腔静脉(IVC)瘤栓的重要手术考虑因素。
BJU Int. 2012 Oct;110(7):926-39. doi: 10.1111/j.1464-410X.2012.11174.x. Epub 2012 Apr 30.
10
Positron emission tomography-computed tomography imaging characteristics of an inferior vena cava tumor thrombus with magnetic resonance imaging correlation.下腔静脉肿瘤血栓的正电子发射断层扫描-计算机断层扫描成像特征及其与磁共振成像的相关性
J Comput Assist Tomogr. 2004 Jul-Aug;28(4):517-9. doi: 10.1097/00004728-200407000-00012.

引用本文的文献

1
Immuno-oncology therapy associated thromboembolic events in metastatic renal cell carcinoma.免疫肿瘤治疗相关的转移性肾细胞癌血栓栓塞事件
Urol Case Rep. 2023 May 3;49:102420. doi: 10.1016/j.eucr.2023.102420. eCollection 2023 Jul.
2
Decoding the multicellular ecosystem of vena caval tumor thrombus in clear cell renal cell carcinoma by single-cell RNA sequencing.通过单细胞 RNA 测序解码透明细胞肾细胞癌下腔静脉癌栓的多细胞生态系统。
Genome Biol. 2022 Mar 31;23(1):87. doi: 10.1186/s13059-022-02651-9.

本文引用的文献

1
Neoadjuvant Sunitinib Decreases Inferior Vena Caval Thrombus Size and Is Associated With Improved Oncologic Outcomes: A Multicenter Comparative Analysis.新辅助舒尼替尼治疗可降低下腔静脉血栓大小并改善肿瘤学预后:一项多中心比较分析。
Clin Genitourin Cancer. 2019 Jun;17(3):e505-e512. doi: 10.1016/j.clgc.2019.01.013. Epub 2019 Jan 30.
2
Rare Case of Intracardiac Renal Cell Carcinoma Metastasis with Response to Nivolumab: Case Report and Literature Review.心脏内肾细胞癌转移并对纳武单抗有反应的罕见病例:病例报告及文献综述
Case Rep Oncol. 2018 Dec 20;11(3):861-870. doi: 10.1159/000495459. eCollection 2018 Sep-Dec.
3
Sunitinib or Sorafenib as Neoadjuvant Therapy May not Improve the Survival Outcomes of Renal Cell Carcinoma with Tumor Thrombus.舒尼替尼或索拉非尼作为新辅助治疗可能无法改善伴有肿瘤血栓的肾细胞癌的生存结局。
Urol Int. 2018;101(4):391-399. doi: 10.1159/000492723. Epub 2018 Sep 5.
4
Updates to the Management of Kidney Cancer.肾癌的治疗进展。
J Natl Compr Canc Netw. 2018 May;16(5S):639-641. doi: 10.6004/jnccn.2018.0039.
5
Check point inhibitors a new era in renal cell carcinoma treatment.检查点抑制剂:肾癌治疗的新时代。
Med Oncol. 2018 May 4;35(6):85. doi: 10.1007/s12032-018-1147-y.
6
[Treatment of Metastatic Renal Cell Carcinoma].[转移性肾细胞癌的治疗]
Klin Onkol. 2018 Spring;31(2):110-116. doi: 10.14735/amko2018110.
7
Role of presurgical targeted molecular therapy in renal cell carcinoma with an inferior vena cava tumor thrombus.术前靶向分子治疗在伴有下腔静脉瘤栓的肾细胞癌中的作用
Onco Targets Ther. 2018 Apr 6;11:1997-2005. doi: 10.2147/OTT.S158114. eCollection 2018.
8
Presurgical pazopanib for renal cell carcinoma with inferior vena caval thrombus: a single-institution study.术前使用帕唑帕尼治疗伴有下腔静脉血栓的肾细胞癌:一项单机构研究。
Anticancer Drugs. 2018 Jul;29(6):565-571. doi: 10.1097/CAD.0000000000000627.
9
[Immunotherapy for renal cell carcinoma - current status].[肾细胞癌的免疫疗法——现状]
Aktuelle Urol. 2018 Apr;49(2):187-191. doi: 10.1055/a-0581-4451. Epub 2018 Mar 27.
10
Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma.纳武利尤单抗联合伊匹木单抗与舒尼替尼治疗晚期肾细胞癌的比较
N Engl J Med. 2018 Apr 5;378(14):1277-1290. doi: 10.1056/NEJMoa1712126. Epub 2018 Mar 21.