肾细胞癌伴下腔静脉肿瘤血栓患者对纳武单抗的强烈反应。
Robust response to nivolumab in patient with renal cell carcinoma inferior vena cava tumour thrombus.
作者信息
Berends Joel, Gourley Eric, Kaushik Dharam
机构信息
Department of Urology, University of Texas Health, San Antonio, Texas, USA.
出版信息
BMJ Case Rep. 2019 Apr 23;12(4):e227030. doi: 10.1136/bcr-2018-227030.
Abstract
A 47-year-old previously healthy man presented with acute moderate flank pain. Evaluation revealed left renal cell carcinoma, with inferior vena cava tumour thrombus invasion. Patient had no significant history or risk factors to pre-dispose him to genitourinary cancers. Surgery was deemed to not be appropriate due to distant metastases, but patient received targeted molecular therapy and immunotherapy with striking regression of the thrombus.
摘要
一名47岁既往健康的男性出现急性中度胁腹疼痛。检查发现左肾细胞癌，伴有下腔静脉肿瘤血栓侵犯。患者无明显病史或危险因素使其易患泌尿生殖系统癌症。由于远处转移，手术被认为不合适，但患者接受了靶向分子治疗和免疫治疗，血栓明显消退。
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