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在无供血、血液制品或人工大分子的极度血液稀释状态下进行心脏手术。

Cardiac surgery in extreme haemodilution without donor blood, blood products or artificial macromolecules.

作者信息

Lilleaasen P, Frøysaker T, Stokke O

出版信息

Scand J Thorac Cardiovasc Surg. 1978;12(3):249-51.

PMID:310160
Abstract

A triple aorto-coronary vein bypass was performed in a 56-year-old Jehovah's Witness. Neither donor blood, albumin nor artificial macromolecules were used. Ten litres of non-haemic fluid were given during surgery and an additional 4 litres during the first 18 postoperative hours. During perfusion the haematocrit fell to 19 vol% and total protein in serum to 29 g/l. Eighteen hours after surgery, the patient was extubated without any signs of oedema and with a positive water balance of only 2.2 l. Diuretics were not given. Acid-base and electrolyte values were within normal limits both during and after operation. This and similar cases reported in the literature show that during extracorporeal circulation it is possible to reduce the concentrations of red cells and plasma proteins to below 40% of pre-operative values without serious complications.

摘要

一位56岁的耶和华见证会信徒接受了一次三支冠状动脉搭桥手术。术中未使用供血、白蛋白或人工大分子物质。手术期间输入了10升无血液体,术后最初18小时又额外输入了4升。灌注期间,血细胞比容降至19%(容积),血清总蛋白降至29g/L。术后18小时,患者拔除气管插管,无任何水肿迹象,正水平衡仅为2.2升。未使用利尿剂。手术期间及术后酸碱和电解质值均在正常范围内。本病例及文献中报道的类似病例表明,在体外循环期间,有可能将红细胞和血浆蛋白浓度降至术前值的40%以下而无严重并发症。

相似文献

1
Cardiac surgery in extreme haemodilution without donor blood, blood products or artificial macromolecules.在无供血、血液制品或人工大分子的极度血液稀释状态下进行心脏手术。
Scand J Thorac Cardiovasc Surg. 1978;12(3):249-51.
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Aortocoronary bypass in Jehovah's Witnesses: review of 46 patients.
Am Surg. 1976 Jan;42(1):17-22.
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Aorto-coronary bypass in Jehovah's Witnesses. Report of 36 patients.
J Thorac Cardiovasc Surg. 1974 Jul;68(1):1-7.
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[A case of aorto-coronary bypass in Jehovah's Witness].[一例耶和华见证人教派信徒接受主动脉冠状动脉搭桥手术的病例]
Kokyu To Junkan. 1989 Jun;37(6):687-90.
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Moderate and extreme haemodilution in open-heart surgery. Blood requirements, bleeding and platelet counts.心脏直视手术中的中度和极度血液稀释。血液需求量、出血情况及血小板计数。
Scand J Thorac Cardiovasc Surg. 1977;11(2):97-103.
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Hypertonic-hyperoncotic solutions improve cardiac function in children after open-heart surgery.高渗高渗胶体溶液可改善儿童心脏直视手术后的心脏功能。
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Open heart operations without transfusion using a multimodality blood conservation strategy in 50 Jehovah's Witness patients: implications for a "bloodless" surgical technique.50例耶和华见证会患者采用多模式血液保护策略进行无输血心脏直视手术:对“无血”手术技术的启示
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Is there really a clinical benefit of using minimized extracorporeal circulation for coronary artery bypass grafting?在冠状动脉旁路移植术中使用体外循环流量最小化真的有临床益处吗?
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Totally minimized extracorporeal circulation: an important benefit for coronary artery bypass grafting in Jehovah's witnesses.完全最小化体外循环:对耶和华见证人教派患者冠状动脉搭桥手术的一项重要益处。
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[Objectives of a bloodless surgery program. A comparative study (major surgery vs. minor-medium surgery) in 51 Jehova's Witnesses patients].[无血手术计划的目标。对51名耶和华见证会患者进行的一项比较研究(大手术与中小手术)]
Ann Ital Chir. 2002 Mar-Apr;73(2):197-209; discussion 209-10.

引用本文的文献

1
Surgery in Jehovah's Witnesses.耶和华见证人的外科手术。
Can J Anaesth. 1989 Sep;36(5):578-85. doi: 10.1007/BF03005389.