Metzger J P, Tabone X, Montgermont P, N'Koua J L, Zannier-Marzari D, Aubry P, Cachera J P, Vacheron A
Arch Mal Coeur Vaiss. 1986 Aug;79(9):1311-7.
Perioperative infarction is a significant factor of morbidity of coronary bypass surgery. The aim of this study was to review peri-operative infarction and its complications over a 10 year period (1974 to 1984) and to determine its consequences on left ventricular function and life expectancy. The material included 514 patients who underwent coronary bypass surgery. Perioperative infarction was defined as the association of a postoperative Q wave and increase in creatinine phosphokinase after the 24th postoperative hour: this diagnosis was made in 31 cases (Group A), 6 per cent of the series; 483 patients (Group B) had no signs of infarction. The necrosis involved the revascularised zone in 26 cases and other zones in 5 cases. The acute phase of infarction was associated with major complications in 9 patients of Group A. In 22 patients (70 per cent of cases) the initial evolution was uncomplicated. There was no significant difference in the number of patients with unstable angina between Groups A and B (52 per cent vs 67 per cent), with single vessel disease (25 per cent vs 28 per cent), double vessel disease (45 per cent vs 34 per cent) or with triple vessel disease (30 per cent vs 38 per cent). The average number of bypasses was higher in Group A (2.06 per cent vs 1.4 per cent, p less than 0.05), as was the duration of cardiopulmonary bypass (117 min vs 91 min, p less than 0.05) and of aortic clamping (45 min vs 31 min, p. less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
围手术期梗死是冠状动脉搭桥手术发病的一个重要因素。本研究的目的是回顾10年期间(1974年至1984年)的围手术期梗死及其并发症,并确定其对左心室功能和预期寿命的影响。研究材料包括514例行冠状动脉搭桥手术的患者。围手术期梗死定义为术后出现Q波且术后24小时后肌酸磷酸激酶升高:31例患者(A组)有此诊断,占该系列病例的6%;483例患者(B组)无梗死迹象。26例梗死累及血管重建区域,5例累及其他区域。A组9例患者的梗死急性期伴有严重并发症。22例患者(占病例的70%)初期病情发展无并发症。A组和B组在不稳定型心绞痛患者数量(52%对67%)、单支血管病变(25%对28%)、双支血管病变(45%对34%)或三支血管病变(30%对38%)方面无显著差异。A组的平均搭桥数量更多(2.06%对1.4%,p<0.05),体外循环时间(117分钟对91分钟,p<0.05)和主动脉阻断时间(45分钟对31分钟,p<0.01)也是如此。(摘要截断于250字)