Biological activity of polychlorinated biphenyls related to conformational structure.
作者信息
McKinney J D, Pedersen L G
出版信息
Biochem J. 1986 Dec 1;240(2):621-2. doi: 10.1042/bj2400621.
Abstract
摘要
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2
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Muscarinic responses and binding in a murine neuroblastoma clone (N1E-115): cyclic GMP formation is mediated by a low affinity agonist-receptor conformation and cyclic AMP reduction is mediated by a high affinity agonist-receptor conformation.小鼠神经母细胞瘤克隆株（N1E-115）中的毒蕈碱反应与结合：环鸟苷酸的形成由低亲和力激动剂-受体构象介导，而环磷酸腺苷的减少由高亲和力激动剂-受体构象介导。
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