[蠕虫与肠道原生动物及肠道微生物群相互作用的研究进展]
[Progress of research on the interplay between helminth and intestinal protozoa and gut microbiota].
作者信息
Meng Xu, Yu-Juan Shen
机构信息
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, National Health Commission, Shanghai 200025, China.
出版信息
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2019 Mar 29;31(1):77-85. doi: 10.16250/j.32.1374.2019005.
As the largest and most complex ecosystem in humans, gut microbiota resides in human or animal gastrointestinal tract with intestinal viruses and parasites. Previous studies have demonstrated that gut microbiotadysbiosis is strongly correlated with the development, progression and prognosis of multiple diseases. The parasites that are colonized in the host, may directly or indirectly affect gut microbiota and the gut microbiota-host homeostasis, and changes in the composition and diversity of gut microbiota may also affect parasitic infections and the development, progression and prognosis of parasitic diseases. This paper reviews the progress of research on the interplay between helminth and intestinal protozoa and gut microbiota.
作为人类体内最大且最复杂的生态系统，肠道微生物群与肠道病毒和寄生虫一同存在于人类或动物的胃肠道中。先前的研究表明，肠道微生物群失调与多种疾病的发生、发展及预后密切相关。寄生于宿主体内的寄生虫可能直接或间接影响肠道微生物群以及肠道微生物群与宿主之间的稳态，而肠道微生物群的组成和多样性变化也可能影响寄生虫感染以及寄生虫病的发生、发展和预后。本文综述了蠕虫、肠道原生动物与肠道微生物群之间相互作用的研究进展。
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