Wu Yun, Li Jian
Pharmacy, People's Liberation Army Southern Theater General Hospital, Guangzhou 510010, P.R.China;College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, P.R.China;Pharmacy, University of Chinese Academy of Sciences Shenzhen Hospital, Shenzhen, Guangdong 518107, P.R.China.
Pharmacy, People's Liberation Army Southern Theater General Hospital, Guangzhou 510010, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2019 Apr 25;36(2):325-333. doi: 10.7507/1001-5515.201805051.
In recent years, due to the dramatic increase in the number of surgical operations, there has been a clinically significant increase in the demand for medical adhesives capable of cohesion in a moist environment that can overcome blood or tissue fluids . As the understanding of the mechanisms and key elements of natural adhesion to aquatic organisms continues to develop, a variety of medical adhesives have been developed by mimicking adhesion procedures or utilizing key functional groups. This article will review the classification, adhesion mechanism, use, research progress and development prospects of biomedical adhesives inspired by aquatic organisms octopus and mussels.
近年来,由于外科手术数量急剧增加,临床上对能够在潮湿环境中实现黏附、克服血液或组织液影响的医用黏合剂的需求显著上升。随着对水生生物自然黏附机制及关键要素的认识不断深入,人们通过模仿黏附过程或利用关键官能团开发出了多种医用黏合剂。本文将综述受章鱼和贻贝等水生生物启发的生物医用黏合剂的分类、黏附机制、用途、研究进展及发展前景。