1 Department of Urology, Stanford University Medical Center, Stanford, California.
2 Department of Urology, Konkuk University School of Medicine, Seoul, Korea.
J Endourol. 2019 Jul;33(7):614-618. doi: 10.1089/end.2019.0154. Epub 2019 May 24.
The objective of this study was to show the prevalence and investigate treatment trends of pediatric nephrolithiasis based on a large population of U.S. insurance individual's data. This research involved a retrospective observational cohort study. Administrative claims data were extracted from the IBM MarketScan Research Database. We included all patients newly diagnosed with nephrolithiasis, aged <18 years old at the time of diagnosis from January 1, 2007, to December 31, 2014. The patient cohort with nephrolithiasis was selected using the International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM) code for nephrolithiasis. Each treatment method was searched by Current Procedural Terminology (CPT) code. A total of 28,014 patients were found to have nephrolithiasis in our cohort. Of nephrolithiasis patients, 701 (2.5%) patients were treated by surgical methods. The mean age of patients at the time of treatment was 13 years old. Extracorporeal shockwave lithotripsy (SWL) was the most used treatment modality during the period. SWL was performed in 66% of patients. The number of cases of SWL did not tend to change according to year, whereas retrograde intrarenal surgery (RIRS) tended to increase from 15% to 31%. Percutaneous nephrolithotripsy (PCNL) decreased from 13% to <10 cases. The number of open surgeries was very small and did not show any tendency. During the study period, SWL is stable. RIRS has become more popular in treating renal stones, whereas PCNL has decreased. These results suggest that the RIRS has become more popular than PCNL in treating large renal stones.
本研究旨在根据美国保险个体的大量数据,展示小儿肾结石的流行情况并探讨其治疗趋势。本研究涉及一项回顾性观察性队列研究。从 IBM MarketScan Research Database 提取行政索赔数据。我们纳入了所有在 2007 年 1 月 1 日至 2014 年 12 月 31 日期间新诊断为肾结石、年龄<18 岁的患者。肾结石患者队列通过肾结石的国际疾病分类,第 9 版,临床修订版(ICD-9-CM)代码选择。每种治疗方法均通过当前程序术语(CPT)代码搜索。在我们的队列中,共发现 28014 例肾结石患者。在肾结石患者中,有 701(2.5%)例患者采用手术方法治疗。患者治疗时的平均年龄为 13 岁。体外冲击波碎石术(SWL)是该期间最常用的治疗方式。SWL 在 66%的患者中进行。SWL 的病例数没有随着年份的变化而变化,而逆行性肾内手术(RIRS)的数量从 15%增加到 31%。经皮肾镜碎石术(PCNL)从 13%减少到<10 例。开放性手术的数量很少,且没有任何趋势。在研究期间,SWL 保持稳定。RIRS 已成为治疗肾结石的更受欢迎方法,而 PCNL 则减少。这些结果表明,RIRS 已成为治疗大肾结石比 PCNL 更受欢迎的方法。