J Oral Facial Pain Headache. 2019 Summer;33(3):e15–e18. doi: 10.11607/ofph.2139. Epub 2019 Apr 24.
Erythermalgia is a rare cutaneous disease characterized by episodic attacks of burning pain, erythema, and increased temperature. It primarily involves the extremities, with possible extensions to the ears, face, neck, and scrotum; in rare instances, it may afflict the ears, face, or the scrotum alone. Although various medications alone or in different combinations have been tried with significant variations in response, no recommended therapeutics have been established until very recently. This report presents two case histories of a 20-year-old and a 46-year-old woman, respectively, who displayed intermittent facial erythema associated with warmth and pain during the episodes and who presented normal between episodes. Both had good response to combinative treatments of systemic medication and topical lidocaine compounds. The younger was disease-free after more than 4 years of follow-up, and the older had recurrence after stopping the treatment. Conclusion: Erythermalgia may involve the face alone, and combinative approaches may be of choice for its treatment. Topical lidocaine compounds are considered to be a good option for palliative treatment.
红斑性肢痛症是一种罕见的皮肤疾病，其特征为阵发性灼热样疼痛、红斑和体温升高。它主要累及四肢，也可能累及耳朵、面部、颈部和阴囊；极少数情况下，耳朵、面部或阴囊可能单独受累。尽管已经尝试了各种单一或联合用药，但反应差异很大，直到最近才确定了推荐的治疗方法。本报告介绍了两例分别为 20 岁和 46 岁女性的病例，她们在发作期间表现为间歇性面部红斑伴灼热和疼痛，发作间期正常。两者均对全身药物治疗和局部利多卡因化合物的联合治疗有良好的反应。年轻患者在随访 4 年多后无病，而年长患者在停止治疗后复发。结论：红斑性肢痛症可能仅累及面部，联合治疗可能是其治疗的选择。局部利多卡因化合物被认为是姑息治疗的良好选择。
