Department of Dermatology, The Eastern Hospital of The First Affiliated Hospital, Sun Yat-sen University, 183 Huangpu Rd, E, Guangzhou 510700, China.
J Headache Pain. 2014 Mar 26;15(1):18. doi: 10.1186/1129-2377-15-18.
Erythermalgia is a rare cutaneous disorder characterized by attacking of erythema, pain and increased temperature, which primarily involves the extremities and may infrequently extend to the neck, face, ears and even the scrotum. We reported an 18-year-old woman who presented with 3 years history of sole involvement of attacking erythema, pain and warmth over her face and ears without any other associations. The frequency and severity of the flares progressed gradually during the course. Cutaneous examination revealed erythema, increased temperature and tenderness on the face and ears during the flare. The symptoms could be relieved rapidly by cooling. Dermatoscope showed that vessels inside the erythema were more dilated during the episode than after application of ice. The lesion is considered a rare variant of erythermalgia with sole involvement of face and ears. The symptoms had mild response to oral antihistamines, topical steroids and tacrolimus, but had excellent response to the combinative therapy of aspirin and paroxetins.
红斑性肢痛症是一种罕见的皮肤疾病，其特征为红斑、疼痛和温度升高，主要涉及四肢，偶尔也会延伸到颈部、面部、耳朵，甚至阴囊。我们报告了一位 18 岁的女性患者，她的面部和耳部出现了 3 年的红斑、疼痛和温热感，但没有其他关联。在病程中，红斑的频率和严重程度逐渐加重。皮肤检查显示，红斑发作时面部和耳部出现红斑、温度升高和压痛。症状可以通过冷却迅速缓解。皮肤镜显示，红斑发作时红斑内的血管比冰敷后扩张得更明显。该病变被认为是红斑性肢痛症的一种罕见变异型，仅累及面部和耳部。症状对口服抗组胺药、局部类固醇和他克莫司有轻微反应，但对阿司匹林和帕罗西汀联合治疗有极好的反应。
