Condren Michelle, Sabet Samie, Chalmers Laura J, Saley Taylor, Hopwood Jenna
J Pediatr Pharmacol Ther. 2019 Mar-Apr;24(2):99-106. doi: 10.5863/1551-6776-24.2.99.
Type 1 diabetes mellitus has witnessed significant progress in its management over the past several decades. This review highlights technologic advancements in type 1 diabetes management. Continuous glucose monitoring systems are now available at various functionality and cost levels, addressing diverse patient needs, including a recently US Food and Drug Administration (FDA)-approved implantable continuous glucose monitoring system (CGMS). Another dimension to these state-of-the-art technologies is CGMS and insulin pump integration. These integrations have allowed for CGMS-based adjustments to basal insulin delivery rates and suspension of insulin delivery when a low blood glucose event is predicted. This review also includes a brief discussion of upcoming technologies such as patch-based CGMS and insulin-glucagon dual-hormonal delivery.
在过去几十年中，1型糖尿病的管理取得了显著进展。本综述重点介绍了1型糖尿病管理中的技术进步。现在有各种功能和成本水平的连续血糖监测系统，可满足不同患者的需求，包括最近美国食品药品监督管理局（FDA）批准的植入式连续血糖监测系统（CGMS）。这些先进技术的另一个方面是CGMS与胰岛素泵的集成。这些集成允许根据CGMS调整基础胰岛素输注率，并在预测到低血糖事件时暂停胰岛素输注。本综述还简要讨论了即将出现的技术，如基于贴片的CGMS和胰岛素-胰高血糖素双激素递送。
