Amoo-Achampong Kelms, Krill Michael K, Acheampong Derrick, Nwachukwu Benedict U, McCormick Frank
Icahn School of Medicine at Mount Sinai, New York, USA.
Department of Orthopaedic Surgery, Duke University, USA.
Shoulder Elbow. 2019 May;11(1 Suppl):4-18. doi: 10.1177/1758573218768099. Epub 2018 Apr 26.
Rotator cuff tear surgical repair techniques have significantly progressed. However, tendon retear following primary repair persistently occurs at high rates. Rehabilitation protocols, surgical fixation techniques, biologic therapy with scaffolds, platelet-rich plasma, and even stem cell applications are under study to promote adequate tendon healing.
A nonsystematic query of the PubMed database was conducted in July 2016 utilizing the search terms "rotator cuff repair," "tear," "rehabilitation," "scaffold," "platelet-rich plasma," and "stem cell" to identify, analyze, and summarize relevant studies.
Individualized rehabilitation protocols may be the best approach for small to medium sized tears. Surgical fixation will continue to be debated as modifications to single-row technique and increases in suture number have improved tensile strength. Double-row repairs have been associated with higher costs. Transosseous equivalent technique exhibits comparable subjective and objective outcomes to single- and double-row repair at two-year follow-up. Biocompatible scaffold augmentation has showed inconsistent short-term results. Platelet-rich plasma has lacked uniformity in treatment preparation, administration, and outcome measurement with mixed results. Few human studies have suggested decreased retear rates and improved repair maintenance following bone marrow-derived mesenchymal stem cell augmentation. This review reiterated the necessity of additional high-quality, large-sample studies to develop any final verdict regarding efficacy.
肩袖撕裂的手术修复技术有了显著进展。然而,初次修复后的肌腱再撕裂发生率仍然很高。目前正在研究康复方案、手术固定技术、使用支架的生物治疗、富血小板血浆,甚至干细胞应用,以促进肌腱充分愈合。
2016年7月,利用搜索词“肩袖修复”“撕裂”“康复”“支架”“富血小板血浆”和“干细胞”对PubMed数据库进行了非系统性检索,以识别、分析和总结相关研究。
对于中小尺寸的撕裂,个体化康复方案可能是最佳方法。随着对单排技术的改进和缝线数量的增加提高了拉伸强度,手术固定仍将存在争议。双排修复的成本更高。在两年随访中,经骨等效技术的主观和客观结果与单排和双排修复相当。生物相容性支架增强术的短期结果并不一致。富血小板血浆在治疗准备、给药和结果测量方面缺乏一致性,结果不一。很少有人类研究表明,骨髓间充质干细胞增强术后再撕裂率降低,修复维持效果改善。这篇综述重申了开展更多高质量、大样本研究以对疗效做出最终定论的必要性。