Jönelid Birgitta, Kragsterman Björn, Berglund Lars, Andrén Bertil, Johnston Nina, Lindahl Bertil, Oldgren Jonas, Christersson Christina
Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.
Department of Surgical Sciences, Vascular Surgery, Uppsala University, Uppsala, Sweden.
JRSM Cardiovasc Dis. 2019 Apr 16;8:2048004019841971. doi: 10.1177/2048004019841971. eCollection 2019 Jan-Dec.
To evaluate whether the Walking Impairment Questionnaire score could identify patients with polyvascular disease in a population with recent myocardial infarction and their association with cardiovascular events during two-year follow-up.
A prospective observational study.
Patients admitted to the acute coronary care unit, the Department of Cardiology, Uppsala University Hospital.
Patients admitted with acute Non-STEMI- or STEMI-elevation myocardial infarction.
The Walking Impairment Questionnaire, developed as a self-administered instrument to assess , , and in patients with peripheral artery disease, predicts future cardiovascular events and mortality. Two hundred and sixty-three patients with recent myocardial infarction answered Walking Impairment Questionnaire. Polyvascular disease was defined as abnormal findings in the coronary- and carotid arteries and an abnormal ankle-brachial index. The calculated score for each of all three categories were divided into quartiles with the lowest score in first quartile.
The lowest (worst) quartile in all three Walking Impairment Questionnaire categories was associated with polyvascular disease, fully adjusted; , odds ratio (OR) 5.4 (95% confidence interval (CI) 1.8-16.1); , OR 7.4 (95% CI 1.5-36.5); , OR 8.4 (95% CI 1.0-73.6). In , patients with the lowest (worst) score had a higher risk for the composite cardiovascular endpoint compared to the highest (best) score; hazard ratio 5.3 (95% CI 1.5-19.0). The adherence to medical treatment was high (between 81.7% and 99.2%).
The Walking Impairment Questionnaire is a simple tool to identify myocardial infarction patients with more widespread atherosclerotic disease and although well treated medically, stair climbing predicts cardiovascular events.
评估步行障碍问卷评分能否在近期心肌梗死患者群体中识别出患有多血管疾病的患者，以及在两年随访期间其与心血管事件的关联。
一项前瞻性观察性研究。
乌普萨拉大学医院心脏病科急性冠脉护理病房收治的患者。
因急性非ST段抬高型或ST段抬高型心肌梗死入院的患者。
步行障碍问卷是一种作为自我管理工具开发的，用于评估外周动脉疾病患者的[具体评估内容缺失]，可预测未来心血管事件和死亡率。263例近期心肌梗死患者回答了步行障碍问卷。多血管疾病定义为冠状动脉和颈动脉存在异常发现以及踝臂指数异常。所有三个类别各自的计算得分被分为四分位数，第一四分位数得分最低。
在所有三个步行障碍问卷类别中，最低（最差）四分位数与多血管疾病相关，经过充分调整；[具体内容缺失]，比值比（OR）5.4（95%置信区间（CI）1.8 - 16.1）；[具体内容缺失]，OR 7.4（95% CI 1.5 - 36.5）；[具体内容缺失]，OR 8.4（95% CI 1.0 - 73.6）。在[具体内容缺失]方面，得分最低（最差）的患者与得分最高（最佳）的患者相比，发生复合心血管终点事件的风险更高；风险比5.3（95% CI 1.5 - 19.0）。药物治疗依从性较高（在81.7%至99.2%之间）。
步行障碍问卷是一种简单的工具，可用于识别患有更广泛动脉粥样硬化疾病的心肌梗死患者，并且尽管接受了良好的药物治疗，但爬楼梯能力可预测心血管事件。
