Wojcikiewicz Thomas G, Jeans John, Karmali Anil, Nkhoma Jackline, Cousins Jonathan, Kynoch Michael
Department of Anaesthesia, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Br J Pain. 2019 May;13(2):106-111. doi: 10.1177/2049463718800521. Epub 2018 Sep 19.
The use of intrathecal diamorphine is not commonplace in laparoscopic bariatric surgery. At our institution, a major UK bariatric centre, high-dose intrathecal diamorphine is routinely utilised.
Data were analysed retrospectively. Fifty-three patients who had a spinal anaesthetic were matched against age, sex, body mass index and surgical procedure type to generate controls. Pain scores were recorded in the post-anaesthetic care unit on arrival, after 1 hour and on discharge to the ward. Post-operative nausea and vomiting; post-operative hypertension; pruritus; 24-hour morphine consumption and length of stay were measured.
Pain scores were better in the spinal anaesthetic group in all measured categories (p = 0.033, p < 0.01, p < 0.01); post-operative nausea and vomiting was less common in the spinal anaesthetic group (p < 0.01); post-operative hypertension was less common in the spinal anaesthetic group (p = 0.25); pruritus was more common in the spinal anaesthetic group (p < 0.01); morphine consumption was less common in the spinal anaesthetic group (p = 0.037). Length of hospital stay was reduced by 12.4 hours (p = 0.025).
We propose that this is a practical and safe technique to adopt. A randomised-control trial will need to be conducted in order to find the most efficacious volume of local anaesthetic and dose of diamorphine.
鞘内注射二醋吗啡在腹腔镜减肥手术中并不常见。在我们机构,一家英国主要的减肥中心,常规使用高剂量鞘内注射二醋吗啡。
对数据进行回顾性分析。将53例接受脊髓麻醉的患者与年龄、性别、体重指数和手术类型相匹配以生成对照组。在麻醉后护理单元记录患者到达时、1小时后和转至病房时的疼痛评分。测量术后恶心和呕吐、术后高血压、瘙痒、24小时吗啡消耗量和住院时间。
在所有测量类别中,脊髓麻醉组的疼痛评分更好(p = 0.033,p < 0.01,p < 0.01);脊髓麻醉组术后恶心和呕吐较少见(p < 0.01);脊髓麻醉组术后高血压较少见(p = 0.25);脊髓麻醉组瘙痒更常见(p < 0.01);脊髓麻醉组吗啡消耗量较少见(p = 0.037)。住院时间缩短了12.4小时(p = 0.025)。
我们认为这是一种实用且安全的技术。需要进行一项随机对照试验,以确定局部麻醉剂的最有效用量和二醋吗啡的剂量。