大鼠乳头丘脑脑啡肽能通路：免疫细胞化学分析

Mammillothalamic enkephalinergic pathway in the rat: an immunocytochemical analysis.

作者信息

Fujii S, Senba E, Kiyama H, Ueda Y, Tohyama M

出版信息

Brain Res. 1987 Jan 13;401(1):1-8. doi: 10.1016/0006-8993(87)91155-3.

PMID:3101977

Abstract

We studied the afferent sources of Leu-enkephalin (ENK) -like immunoreactive (ENKI) fibers in the anteroventral thalamic nucleus (AV) of the rat using experimental immunohistochemistry. These fibers were markedly fewer on the operated side after the destruction of the medial mammillary nucleus pars medialis where a number of ENKI cells were observed. This strongly suggests that these ENKI cells project ipsilaterally to the AV. ENKI fibers seemed to reach the AV via the mammillothalamic tract.

摘要

我们采用实验性免疫组织化学方法，研究了大鼠丘脑前腹核（AV）中亮氨酸脑啡肽（ENK）样免疫反应性（ENKI）纤维的传入来源。在内侧乳头体核内侧部被破坏后，手术侧的这些纤维明显减少，在此处观察到许多ENKI细胞。这有力地表明，这些ENKI细胞同侧投射至AV。ENKI纤维似乎经乳头丘脑束到达AV。