IEEE Trans Biomed Eng. 2020 Jan;67(1):268-276. doi: 10.1109/TBME.2019.2912407. Epub 2019 Apr 22.
Biomedical wearable sensors enable long-term monitoring applications and provide instantaneous diagnostic capabilities. Physiological monitoring can help in both the diagnosis and the ongoing treatment of a vast number of cardiovascular and pulmonary diseases such as hypertension, dysrhythmia, and asthma. In this paper, we present a system capable of monitoring several vital signals and physiological variables that determine the cardiopulmonary activity status. We explore direct measurements of multiple vital parameters with only one sensor and without special constraints. The system employs a PZT-4 piezo transducer stimulated by a suitable analog front end. The system both generates pulsed ultrasound waves at 1 MHz and amplifies reflected echoes to track internal organ motions, mainly that of the heart apex. According to the respiratory motion of the heart, the proposed system provides respiratory and heart cycles information. Promising results were obtained from six subjects with an average accuracy of 96.7% in heartbeats per minute measurement, referenced to a commercial photoplethysmography sensor. It also exhibits 94.5% sensitivity and 94.0% specificity in respiration detection compared to a spirometer signal as a reference.
生物医学可穿戴传感器能够实现长期监测应用,并提供即时诊断功能。生理监测有助于诊断和持续治疗大量心血管和肺部疾病,如高血压、心律失常和哮喘。在本文中,我们提出了一种能够监测多个决定心肺活动状态的重要信号和生理变量的系统。我们探索了仅使用一个传感器和没有特殊约束条件的多种重要参数的直接测量方法。该系统采用 PZT-4 压电换能器,由合适的模拟前端激励。该系统既能产生 1MHz 的脉冲超声波,又能放大反射回波以跟踪内部器官运动,主要是心脏尖部的运动。根据心脏的呼吸运动,该系统提供呼吸和心跳周期信息。从六位受试者中获得了有希望的结果,与商业光电容积脉搏传感器相比,每分钟心跳测量的平均准确率为 96.7%。与作为参考的肺活量计信号相比,它在呼吸检测方面的灵敏度为 94.5%,特异性为 94.0%。