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[结肠癌和直肠癌的早期检测;潜血的广泛研究]

[Early detection of colonic and rectal cancer; extensive study of occult blood].

作者信息

Jorge A D, Sánchez D, Díaz M, Lorenzo J, Milutin C

出版信息

Acta Gastroenterol Latinoam. 1977 Dec;7(4):261-8.

PMID:310229
Abstract

Due to the high frequency and usually late diagnosis of cancer of colon and rectum the "haemoccult test" has been recommended as an easy, quick, and unexpensive method for stool determination of occult blood that will allow us to suspect the existence of these tumors in their early asymptomatic stages. The test was performed in 1437 patients attending the gastroenterology clinic which had no clinical evidence of bleeding, of these, 1150 returned the samples. In 52 (4,6%) the test was positive for occult blood. The studies performed revelated that 4 were upper gastrointestinal ilions, one ileal diverticulum and 40 (3,47%) patients had colonic disease of the latter 19 were diverticular disease, 1 crohnis disease of rectum, 2 adenomatous and 2 villous polips, 1 Hodkgin disease and 7 carcinomas. There were 6 false positive results. The high frequency of positive "haemoccult test" in colonic disease, specially benign and malignant tumors, make this test and appropiate method of this time in the detection for colo-rectal carcinoma.

摘要

由于结肠癌和直肠癌的高发病率以及通常较晚的诊断,“潜血试验”被推荐为一种简单、快速且廉价的粪便潜血检测方法,这将使我们能够在这些肿瘤早期无症状阶段怀疑其存在。对1437名到胃肠病诊所就诊且无临床出血证据的患者进行了该检测,其中1150人返回了样本。52人(4.6%)潜血试验呈阳性。所进行的研究表明,4人患有上消化道疾病,1人患有回肠憩室,40人(3.47%)患有结肠疾病,其中19人患有憩室病,1人患有直肠克罗恩病,2人患有腺瘤性息肉和2人患有绒毛状息肉,1人患有霍奇金病,7人患有癌症。有6例假阳性结果。结肠疾病(特别是良性和恶性肿瘤)中“潜血试验”阳性的高频率使得该检测成为目前检测结直肠癌的一种合适方法。

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