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结肠癌筛查试验——新的比较:潜血试验 - 血红蛋白粪便免疫化学试验以及潜血试验9年临床经验回顾(作者译)

[Screening tests for colon cancer - a new comparison Haemoccult - hemoFEC and review of 9 years clinical experience with Haemoccult (author's transl)].

作者信息

Gnauck R

出版信息

Z Gastroenterol. 1982 Feb;20(2):84-92.

PMID:6977955
Abstract

Haemoccult was compared once more with hemoFEC after improvements of the latter material in 1979. 3200 patients were tested parallel with both materials. Haemoccult was positive in 149 patients = 4.6%, hemoFEC was positive in 129 patients = 4.0%. With Haemoccult 22 cancers and 26 large polyps were traced, with hemoFEC 20 cancers and 25 adenomas. 2 cancers and 19 large polyps were negative with both tests. Since 1972 a total of 25.700 patients have been tested with Haemoccult as part of the routine check-program, 873 = 3.4% had a positive test. Of the 600 examined, 124 had colorectal cancer and 196 had a large polyp. By reviewing the charts of all cancers and polyps diagnosed, 19 out of 143 cancers = 13% and 136 out of 332 polyps = 41% had a false-negative Haemoccult test on one-time, initial testing.

摘要

1979年对血隐(Haemoccult)与粪隐血免疫检测法(hemoFEC)进行了再次比较,后者在此之前已得到改进。3200名患者同时接受了这两种检测。血隐检测呈阳性的有149例患者,占4.6%;粪隐血免疫检测法呈阳性的有129例患者,占4.0%。血隐检测发现了22例癌症和26个大息肉,粪隐血免疫检测法发现了20例癌症和25个腺瘤。两种检测均呈阴性的有2例癌症和19个大息肉。自1972年以来,共有25700名患者接受了血隐检测,作为常规检查项目的一部分,检测呈阳性的有873例,占3.4%。在接受检查的600例患者中,124例患有结直肠癌,196例有大息肉。通过查阅所有确诊癌症和息肉的病历,在143例癌症中有19例(占13%)、在332例息肉中有136例(占41%)在首次一次性检测时血隐检测呈假阴性。

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