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用于时间分辨生物应用的理性设计的细胞器特异性热激活延迟荧光小分子有机探针。

Rationally designed organelle-specific thermally activated delayed fluorescence small molecule organic probes for time-resolved biological applications.

机构信息

State Key Laboratory of Bioactive Substances and Function of Natural Medicine, Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 1 Xian Nong Tan Street, Beijing, 100050, China.

出版信息

Chem Commun (Camb). 2019 May 9;55(39):5639-5642. doi: 10.1039/c9cc00898e.

DOI:10.1039/c9cc00898e
PMID:31025673
Abstract

Two organelle-specific small molecule organic thermally activated delayed fluorescence (TADF) probes were developed, which exhibited the longest average fluorescence lifetime in time-resolved fluorescence imaging studies of cells among so far reported TADF probes.

摘要

两种细胞器特异性小分子有机热激活延迟荧光 (TADF) 探针被开发出来,在迄今为止报道的 TADF 探针中,它们在细胞的时间分辨荧光成像研究中表现出最长的平均荧光寿命。

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