Department of Forensic Medicine, All India Institute of Medical Sciences, New Delhi, 110029, India.
Department of Forensic Medicine, ESIC Medical College, Faridabad, Haryana, 121001, India.
Arch Womens Ment Health. 2019 Dec;22(6):771-777. doi: 10.1007/s00737-019-00964-6. Epub 2019 Apr 26.
The purpose of the study was to determine the phases of the menstrual cycle in the reproductive age group of females who committed suicide as compared with a control group of females who died from causes other than suicide. The study included 86 cases in the suicidal group and 80 cases in the non-suicidal group. The menstrual phase was decided by the gross and histological examination of the uterus and ovary at autopsy. Deaths were more common during the secretory phase (56.9%) in the suicidal group, while in the non-suicidal group, death occurred more commonly in the proliferative phase (66.3%). In reference to proliferative phase, deaths were more in the secretory phase and menstrual phase in the suicidal group, adjusted odd's ratio (OR) being 3.7 (p = 0.042) and 4.7 (p = 0.032), respectively. Corpus luteum was present in the right ovary of 43 and 14 victims of suicidal and non-suicidal deaths, respectively, while it was in the left ovary of 3 and 11 victims of suicidal and non-suicidal death, respectively. Odd's ratio was 10.3 for corpus luteum to be in the right ovary in comparison with the left ovary for the suicidal group (p = 0.001). This study revealed that suicidal chances in a woman are significantly more in the menstrual phase and the secretory phase of the menstrual cycle. The presence of corpus luteum in the right ovary is associated with an increased risk of suicide, but the reason is not known.
本研究旨在比较自杀女性和非自杀女性（因自杀以外的原因死亡）生殖年龄段的月经周期阶段。研究包括自杀组 86 例和非自杀组 80 例。月经阶段通过尸检时子宫和卵巢的大体和组织学检查来确定。自杀组中，分泌期（56.9%）死亡更为常见，而非自杀组中，增生期（66.3%）死亡更为常见。与增生期相比，自杀组中死亡更多发生在分泌期和月经期，调整后的优势比（OR）分别为 3.7（p=0.042）和 4.7（p=0.032）。自杀和非自杀死亡的 43 名和 14 名受害者的右侧卵巢中分别存在黄体，而自杀和非自杀死亡的 3 名和 11 名受害者的左侧卵巢中分别存在黄体。与左侧卵巢相比，右侧卵巢中黄体存在的优势比为 10.3（自杀组，p=0.001）。本研究表明，女性在月经期和分泌期自杀的可能性显著增加。右侧卵巢黄体的存在与自杀风险增加相关，但原因尚不清楚。
