Department of Cardiovascular Surgery, China-Japan Friendship Hospital, Beijing 100029, China.
Department of Vascular Surgery, Daqing Oilfield General Hospital, Daqing, 16300, China.
Arch Iran Med. 2019 Mar 1;22(3):132-136.
The optimal management for patients with concomitant severe coronary artery disease (CAD) and carotid artery stenosis (CAS) remains controversial. We reported our preliminary experience on a synchronous hybrid strategy.
Seven patients with synchronous percutaneous coronary intervention (PCI)/carotid endarterectomy (CEA)/coronary artery bypass grafting (CABG) and 36 patients with synchronous CEA/CABG were enrolled. Then we analyzed the demographics, risk factors and 30-day results of the 2 groups, retrospectively.
The 2 groups were comparable in demographics. The operation time was 312.14 ± 40.08 minutes for synchronous PCI/ CEA/CABG and 294.58 ± 47.62 minutes for synchronous CEA/CABG (P = 0.367). The intraoperative blood loss was 814.29±195.18 mL for synchronous PCI/CEA/CABG and 769.44 ± 330.21 mL for synchronous CEA/CABG (P = 0.731). There was no death in the 2 groups within 30 days. The incidence of primary endpoint [stroke, myocardial infarction (MI) and death] was 14.29% (1/7) in synchronous PCI/CEA/CABG group and 5.56% (2/36) in synchronous CEA/CABG group. The difference between the 2 groups was not statistically significant (P = 0.421).
Synchronous PCI, CEA and CABG may be safe and effective in the management of patients with concomitant CAS and complicated multi-vessel CAD. The current data suggested that more studies and randomized controlled trials may be necessary to define whether this strategy is suitable for these patients.
同时患有严重冠状动脉疾病(CAD)和颈动脉狭窄(CAS)的患者的最佳治疗方案仍存在争议。我们报告了采用同步杂交策略的初步经验。
纳入 7 例同期行经皮冠状动脉介入治疗(PCI)/颈动脉内膜切除术(CEA)/冠状动脉旁路移植术(CABG)和 36 例同期 CEA/CABG 的患者。回顾性分析两组患者的人口统计学资料、危险因素和 30 天结果。
两组患者的人口统计学资料无差异。同期 PCI/CEA/CABG 组的手术时间为 312.14±40.08 分钟,同期 CEA/CABG 组为 294.58±47.62 分钟(P=0.367)。同期 PCI/CEA/CABG 组术中出血量为 814.29±195.18ml,同期 CEA/CABG 组为 769.44±330.21ml(P=0.731)。两组患者在 30 天内均无死亡。同期 PCI/CEA/CABG 组的主要终点事件(卒中、心肌梗死(MI)和死亡)发生率为 14.29%(1/7),同期 CEA/CABG 组为 5.56%(2/36),两组间差异无统计学意义(P=0.421)。
同期 PCI、CEA 和 CABG 治疗同时伴有 CAS 和复杂多支 CAD 的患者可能是安全有效的。目前的数据表明,可能需要更多的研究和随机对照试验来确定该策略是否适用于这些患者。