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Cervical Cancer Screening Services at Tertiary Healthcare Facility: An Alternative Approach.三级医疗机构的宫颈癌筛查服务:一种替代方法。
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2
A Study of Pap Smears in HIV-Positive and HIV-Negative Women from a Tertiary Care Center in South India.印度南部一家三级医疗中心对HIV阳性和HIV阴性女性宫颈涂片的研究。
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Amplification of specific chromosomal regions assessed by fluorescent in situ hybridization on Pap smears to be added as screening tool for identifying women at risk of progressing to cervical cancer.通过对巴氏涂片进行荧光原位杂交评估特定染色体区域的扩增,将其作为一种筛查工具,用于识别有进展为宫颈癌风险的女性。
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The prevelance of human papillomavirus (HPV) genotypes detected by PCR in women with normal and abnormal cervico-vaginal cytology.通过聚合酶链反应(PCR)检测正常和异常宫颈阴道细胞学的女性中人乳头瘤病毒(HPV)基因型的流行情况。
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Follow-up of women with cervical cytological abnormalities showing atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion: a nationwide cohort study.对显示意义不明确的非典型鳞状细胞或低级别鳞状上皮内病变的宫颈细胞学异常女性的随访:一项全国性队列研究。
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Punch biopsy guided by both colposcopy and HR-HPV status is more efficient for identification of immediate high-grade squamous intraepithelial lesion or worse among HPV-infected women with atypical squamous cells of undetermined significance.在具有意义不明确的非典型鳞状细胞的HPV感染女性中,由阴道镜检查和HR-HPV状态引导的穿刺活检对于识别即刻高级别鳞状上皮内病变或更严重病变更有效。
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Cervical Cancer: Formulation and Implementation of Govt of India Guidelines for Screening and Management.宫颈癌:印度政府筛查与管理指南的制定与实施
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Call for Systematic Population-Based Cervical Cancer Screening: Findings from Community-Based Screening Camps in Tamil Nadu, India.呼吁开展基于人群的系统性宫颈癌筛查:印度泰米尔纳德邦社区筛查营地的调查结果
Asian Pac J Cancer Prev. 2019 Dec 1;20(12):3703-3710. doi: 10.31557/APJCP.2019.20.12.3703.

本文引用的文献

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Epidemiology of cervical cancer with special focus on India.宫颈癌的流行病学,特别关注印度。
Int J Womens Health. 2015 Apr 16;7:405-14. doi: 10.2147/IJWH.S50001. eCollection 2015.
2
The cervical cancer epidemic that screening has prevented in the UK.在英国,筛查预防的宫颈癌流行情况。
Lancet. 2004;364(9430):249-56. doi: 10.1016/S0140-6736(04)16674-9.
3
Organised vs. spontaneous Pap-smear screening for cervical cancer: A case-control study.宫颈癌的组织性与自发性巴氏涂片筛查:一项病例对照研究。
Int J Cancer. 1999 Sep 24;83(1):55-8. doi: 10.1002/(sici)1097-0215(19990924)83:1<55::aid-ijc11>3.0.co;2-u.
4
Accelerated decline in cervical cancer mortality in England and Wales.英格兰和威尔士宫颈癌死亡率加速下降。
Lancet. 1995 Dec 9;346(8989):1566-7. doi: 10.1016/s0140-6736(95)92099-4.
5
Cervical cancer detection in British Columbia. A progress report.不列颠哥伦比亚省的宫颈癌检测。进展报告。
J Obstet Gynaecol Br Commonw. 1968 Apr;75(4):392-404. doi: 10.1111/j.1471-0528.1968.tb00136.x.
6
Trends in mortality from cervical cancer in the Nordic countries: association with organised screening programmes.北欧国家宫颈癌死亡率趋势:与有组织的筛查计划的关联。
Lancet. 1987 May 30;1(8544):1247-9. doi: 10.1016/s0140-6736(87)92695-x.
7
Effect of organized screening on incidence and mortality of cervical cancer in Denmark.丹麦有组织的筛查对宫颈癌发病率和死亡率的影响。
Cancer Res. 1989 Apr 15;49(8):2157-60.
8
Effect of a mass screening program on the risk of cervical cancer.大规模筛查计划对宫颈癌风险的影响。
Am J Epidemiol. 1976 May;103(5):512-7. doi: 10.1093/oxfordjournals.aje.a112253.

三级医疗机构的宫颈癌筛查服务:一种替代方法。

Cervical Cancer Screening Services at Tertiary Healthcare Facility: An Alternative Approach.

作者信息

Dhanasekaran Kavitha, Verma Chandresh, Kumar Vipin, Hariprasad Roopa, Gupta Ruchika, Gupta Sanjay, Mehrotra Ravi

机构信息

ICMR-National Institute of Cancer Prevention and Research, Noida, UP, India. Email:

出版信息

Asian Pac J Cancer Prev. 2019 Apr 29;20(4):1265-1269. doi: 10.31557/APJCP.2019.20.4.1265.

DOI:10.31557/APJCP.2019.20.4.1265
PMID:31030504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6948876/
Abstract

Introduction: India fights massive cervical cancer burden. This article highlights an innovative feasible approach enabling tertiary hospitals to contribute to cancer prevention without compromising their primary mandate to provide treatment. Methodology: Since 1979, National Institute of Cancer Prevention and Research (NICPR) support a tertiary hospital in cervical cancer screening through a satellite clinic. Record review of 5328 attendees of this clinic between January-December 2016 was done. Pap-smear testing and reporting were performed by trained NICPR personnel. Patients’ demographics, reproductive history, Pap-test date, cytology results were recorded and results were communicated to respective units for further management. Results: Among 5328 women screened, 2% (96/5328) had abnormal cytology, which included malignancy(33%; 32/96), Atypical Squamous Cells-Undetermined Significance(ASC-US) (20%; 19/96), Atypical Glandular Cells(AGC) (23%; 22/96) with complaints of pain in lower abdomen 65.6%(59/90), white discharge per vaginum 46.7%(42/90) and backache 23.3%(21/90). In which, Muslims- 67% (65/96), illiterates- 58% (56/96). Age>35(p<0.001), parity>3(p<0.05), illiteracy (p<0.05), Muslim women (p<0.05) had positive association with abnormal cytology. Conclusion: Awareness about cervical cancer screening is the immediate need in resource-limited countries. Government hospitals in such countries should house dedicated preventive oncology unit for cancer screening.

摘要

引言

印度面临着巨大的宫颈癌负担。本文重点介绍了一种创新可行的方法,使三级医院能够在不影响其提供治疗的主要任务的前提下,为癌症预防做出贡献。方法:自1979年以来,国家癌症预防与研究所在一家三级医院通过卫星诊所支持宫颈癌筛查工作。对该诊所2016年1月至12月期间的5328名就诊者进行了记录回顾。巴氏涂片检测和报告由经过培训的国家癌症预防与研究所工作人员进行。记录了患者的人口统计学信息、生育史、巴氏检测日期、细胞学结果,并将结果传达给各个科室以便进一步处理。结果:在5328名接受筛查的女性中,2%(96/5328)的细胞学检查异常,其中包括恶性肿瘤(33%;32/96)、意义不明确的非典型鳞状细胞(ASC-US)(20%;19/96)、非典型腺细胞(AGC)(23%;22/96),有65.6%(59/90)的患者主诉下腹部疼痛,46.7%(42/90)的患者有阴道白带异常,23.3%(21/90)的患者有背痛。其中,穆斯林女性占67%(65/96),文盲占58%(56/96)。年龄>35岁(p<0.001)、产次>3次(p<0.05)、文盲(p<0.05)、穆斯林女性(p<0.05)与细胞学异常呈正相关。结论:在资源有限的国家,提高对宫颈癌筛查的认识是当务之急。这些国家的政府医院应设立专门的预防肿瘤科室进行癌症筛查。