Consultant Psychiatrist,UGC Salud Mental,Hospital Universitario Virgen Macarena,Seville,Spain.
Resident Pharmacist,UGC Farmacia,Hospital Universitario Virgen Macarena,Seville,Spain.
Br J Psychiatry. 2019 Aug;215(2):447-448. doi: 10.1192/bjp.2019.102. Epub 2019 Apr 29.
Ketamine therapy for treatment-resistant depression in European national health systems may only be considered after attempting all evidence-based antidepressant strategies outlined in clinical guidelines. This paper seeks to explain the ethical, regulatory and procedural framework for the off-label use of ketamine for treatment-resistant depression within a public healthcare system.Declaration of interestNone.
在欧洲国家卫生系统中，只有在尝试了临床指南中列出的所有基于证据的抗抑郁策略后，才可以考虑使用氯胺酮治疗治疗抵抗性抑郁症。本文旨在解释在公共医疗保健系统中，氯胺酮治疗治疗抵抗性抑郁症的标签外使用的伦理、监管和程序框架。
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