Pathobiology and Immunology Division, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Pathobiology and Immunology Division, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97006, USA.
Trends Immunol. 2019 May;40(5):375-377. doi: 10.1016/j.it.2019.03.008.
Long-term drug therapy for HIV-1 infection can prevent both disease progression and virus transmission, but treatment does not eradicate the virus. A new gene therapy study (Immunity 2019;50:567-575.e5) using human antibodies shows significant promise for a functional cure in a non-human primate model.
长期的 HIV-1 感染药物治疗既能预防疾病进展，也能阻止病毒传播，但无法彻底清除病毒。一项新的基因治疗研究（《免疫》2019 年；50：567-575.e5）利用人源抗体，在非人类灵长类动物模型中显示出了实现功能性治愈的巨大潜力。
