Department of Radiology, Seoul National University Hospital, Seoul, Korea; Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
Department of Radiology, Seoul National University Hospital, Seoul, Korea; Department of Radiology, Seoul National University College of Medicine, Seoul, Korea; Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea.
Ultrasound Med Biol. 2019 Jul;45(7):1594-1602. doi: 10.1016/j.ultrasmedbio.2019.03.007. Epub 2019 Apr 25.
The clinical value of the reliability measurement index (RMI), newly added to point shear wave elastography (pSWE), was investigated. Forty-nine patients underwent both pSWE providing RMI (range: 0.0-1.0) and transient elastography (TE) before hepatic surgery. Interclass correlation coefficients (ICCs) between the median of the first two to nine measurements (as categorized by RMI values ≥0.0 (liver stiffness-reliability measurement index [LS-RMI] 0.0), ≥0.4 (LS-RMI 0.4) and ≥0.7 (LS-RMI 0.7) and the median of 10 consecutive measurements (LS-REF) were obtained. Compared with LS-REF, minimums of 7 LS-RMI 0.0, 5 LS-RMI 0.4 and 3 LS-RMI 0.7 measurements were required to obtain an ICC ≥0.95 with high inter-observer agreement (ICC ≥0.90). Diagnostic performance did not differ (p values >0.05) using these reduced numbers of LS measurements. Significant correlations were found between the reduced number of LS measurements and TE or METAVIR (p values <0.001). Therefore, RMI helped to improve reliability and reduce the number of LS measurements while maintaining the diagnostic performance of pSWE.
研究了新加入的可靠性测量指标（RMI）在瞬时弹性成像（TE）中的临床价值。49 名患者在肝手术前均进行了提供 RMI（范围：0.0-1.0）的 pSWE 和 TE。通过 RMI 值≥0.0（肝硬度可靠性测量指标 [LS-RMI] 0.0）、≥0.4（LS-RMI 0.4）和≥0.7（LS-RMI 0.7）将前两次至第九次测量的中位数（分类），获得了第一个中位数与 10 次连续测量的中位数（LS-REF）之间的组内相关系数（ICC）。与 LS-REF 相比，需要 7 次 LS-RMI 0.0、5 次 LS-RMI 0.4 和 3 次 LS-RMI 0.7 测量，才能获得具有高观察者间一致性（ICC≥0.90）的 ICC≥0.95。使用这些减少的 LS 测量值，诊断性能没有差异（p 值>0.05）。减少的 LS 测量值与 TE 或 METAVIR 之间存在显著相关性（p 值<0.001）。因此，RMI 有助于提高可靠性并减少 LS 测量次数，同时保持 pSWE 的诊断性能。
