Advanced Clinical Pharmacist - Electronic Prescribing, Pharmacy Department, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, B15 2TH, England, United Kingdom.
Best Pract Res Clin Obstet Gynaecol. 2019 May;57:106-119. doi: 10.1016/j.bpobgyn.2019.03.006. Epub 2019 Apr 3.
This review aims to summarise historic and the latest evidence of commonly used drugs in pregnant women with chronic kidney disease (CKD). Data regarding safety of drugs in breastfeeding are also described. Practical recommendations are made on the use of newer agents that have limited information of use in pregnant women with CKD. Pharmacokinetic and dynamic issues are outlined, and general principles for prescribing drugs in pregnant women with CKD are listed. Resources to investigate drug safety are presented.
这篇综述旨在总结慢性肾脏病（CKD）孕妇中常用药物的历史和最新证据。还描述了哺乳期药物安全性的数据。对在 CKD 孕妇中使用信息有限的新型药物提出了实用建议。概述了药代动力学和动力学问题，并列出了 CKD 孕妇处方药物的一般原则。还介绍了调查药物安全性的资源。
