Williams T C, Frohman L A
Pharmacotherapy. 1986 Nov-Dec;6(6):311-8. doi: 10.1002/j.1875-9114.1986.tb03493.x.
Growth hormone (GH) previously was available in limited supply and only for the treatment of GH-deficient children. The recent production of GH by recombinant DNA technology has provided a potential surfeit of this hormone and raises the possibility of its use in other conditions. In addition, the isolation, characterization, and synthesis of GH-releasing hormone (GRH) provides an opportunity to use this peptide in conditions in which increased circulating levels of GH are desired. Both GH and GRH have potential therapeutic uses in conditions other than growth retardation.
生长激素（GH）以前供应有限，仅用于治疗生长激素缺乏的儿童。最近通过重组DNA技术生产生长激素，使这种激素可能出现供应过剩的情况，并增加了其在其他病症中应用的可能性。此外，生长激素释放激素（GRH）的分离、表征和合成，为在需要提高循环中生长激素水平的病症中使用这种肽提供了机会。生长激素和生长激素释放激素在生长迟缓以外的病症中都有潜在的治疗用途。
