Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA.
Muscle Nerve. 2019 Aug;60(2):155-160. doi: 10.1002/mus.26499. Epub 2019 May 11.
Existing normal value references for pediatric nerve conduction studies (NCS) are based on limited sample sizes with uncertain reliability, suggesting a need for better normative data.
Electronic medical records were reviewed for pediatric patients (0 to <18 years) with normal findings on electromyography and NCS during the period from January 1, 1997 through September 20, 2017. Electrodiagnostic and demographic data were collected. Gaussian and descriptive statistics were used to establish normal values by age group.
In this study we analyzed 1,918 normal NCS on 1,849 unique pediatric patients. Patients were stratified by age: 0 to <1 month; 1 to <6 months; 6 to <12 months; 12 to <24 months; 2 to <3 years; 3 to <4 years; 4 to <5 years; 5 to <10 years; 10 to <15 years; and 15 to <18 years. Normal reference ranges for amplitude, conduction velocity, and distal latency were established for each age group for 4 motor and 4 sensory nerves.
The large sample size of this study provides reliable reference values for interpreting pediatric NCS. Muscle Nerve 60: 155-160, 2019.
现有的儿科神经传导研究(NCS)正常参考值基于有限的样本量,可靠性不确定,这表明需要更好的规范数据。
对 1997 年 1 月 1 日至 2017 年 9 月 20 日期间接受肌电图和 NCS 检查且结果正常的儿科患者(0 至<18 岁)的电子病历进行了回顾。收集了电诊断和人口统计学数据。使用高斯分布和描述性统计来按年龄组建立正常值。
在这项研究中,我们分析了 1849 例独特的儿科患者的 1918 例正常 NCS。患者按年龄分层:0 至<1 个月;1 至<6 个月;6 至<12 个月;12 至<24 个月;2 至<3 岁;3 至<4 岁;4 至<5 岁;5 至<10 岁;10 至<15 岁;和 15 至<18 岁。为每个年龄组的 4 条运动神经和 4 条感觉神经建立了幅度、传导速度和远端潜伏期的正常参考范围。
本研究的样本量大,为解释儿科 NCS 提供了可靠的参考值。《肌肉与神经》60:155-160,2019 年。