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分析用于预测临床肝移植结局的供体标准。

Analysis of donor criteria for the prediction of outcome in clinical liver transplantation.

作者信息

Makowka L, Gordon R D, Todo S, Ohkohchi N, Marsh J W, Tzakis A G, Yokoi H, Ligush J, Esquivel C O, Satake M

出版信息

Transplant Proc. 1987 Feb;19(1 Pt 3):2378-82.

PMID:3103296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2903845/
Abstract

The results of 219 orthotopic human liver transplants performed during 1985 at the University of Pittsburgh were reviewed to determine whether donor parameters could be used to predict the quality of early graft function. Multivariate discriminant analysis demonstrated that traditional parameters of donor assessment are unreliable predictors of poor graft function. Furthermore, 56% of the donors considered poor by conservative selection criteria produced livers with good early posttransplant function. Survival of recipients of primary allografts from donors rated poor was no different than survival of recipients of allografts from donors rated good.

摘要

回顾了1985年在匹兹堡大学进行的219例原位人类肝脏移植的结果,以确定供体参数是否可用于预测早期移植物功能的质量。多变量判别分析表明,传统的供体评估参数并不能可靠地预测移植物功能不良。此外,按照保守选择标准被认为质量较差的供体中,有56%的供体所提供的肝脏在移植后早期功能良好。来自评级为差的供体的初次同种异体移植物受者的生存率与来自评级为好的供体的同种异体移植物受者的生存率并无差异。

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