Department of Plastic and Reconstructive Surgery, Hospital of the Barmherzige Brüder, Paracelsus Medical University Salzburg, Kajetanerplatz 1, 5020, Salzburg, Austria.
Lasers Surg Med. 2020 Feb;52(2):159-165. doi: 10.1002/lsm.23089. Epub 2019 Apr 29.
Extracorporeal shockwave therapy (ESWT) has been demonstrated as a feasible noninvasive method to improve wound healing. This effect was demonstrated to result from increased perfusion and angiogenesis due to systemic growth factor expression. We, therefore, hypothesized that preoperative ESWT reduces scar formation after surgery.
A prospective, controlled pilot study on 24 patients undergoing abdominoplasty was conducted and the efficacy of preoperative unfocused, low energy EWST was evaluated. The right and left half of the operative area were randomly allocated to ESWT or placebo treatment in intrapatient control design. At 6 and 12 weeks after surgery, scar formation was evaluated by 19 different scar parameters included in the patient, observer scar assessment, and the Vancouver scar scale.
The overall rating of the Vancouver and POSAS scale with Mann-Whitney (MW) analysis revealed a clear trend favoring ESWT. At week 6, 7 of 19 parameters clearly favored ESWT (MW > 0.53). At week 12, 8 of 19 parameters clearly favored ESWT. The largest differences were observed in thickness and overall impression (Vancouver scar scale).
ESWT presumably reduces scar formation and postoperative symptoms after abdominoplasty surgery. Further studies are required to confirm ESWT efficacy with statistical significance. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.
体外冲击波疗法(ESWT)已被证明是一种可行的无创方法,可促进伤口愈合。这种效果是由于全身生长因子表达导致灌注和血管生成增加而产生的。因此,我们假设术前 ESWT 可减少手术后的疤痕形成。
对 24 例行腹部整形术的患者进行了前瞻性、对照性的初步研究,并评估了术前非聚焦、低能量 EWST 的疗效。采用患者内对照设计,将手术区域的右侧和左侧随机分配至 ESWT 或安慰剂治疗。术后 6 周和 12 周,通过 19 项不同的疤痕参数评估疤痕形成情况,包括患者、观察者的疤痕评估和温哥华疤痕量表。
温哥华和 POSAS 量表的整体评分通过曼-惠特尼(MW)分析显示,ESWT 具有明显的优势。在第 6 周,19 个参数中有 7 个明显有利于 ESWT(MW>0.53)。在第 12 周,19 个参数中有 8 个明显有利于 ESWT。观察到的最大差异在厚度和整体印象(温哥华疤痕量表)。
ESWT 可能减少腹部整形术后的疤痕形成和术后症状。需要进一步的研究来证实 ESWT 的疗效具有统计学意义。激光外科学杂志。© 2019 威利父子公司