晚期霍奇金病化疗期间的免疫监测。
Immunological monitoring during chemotherapy for advanced Hodgkin's disease.
作者信息
Alexopoulos C G, Wiltshaw E
出版信息
Cancer. 1978 Dec;42(6):2631-40. doi: 10.1002/1097-0142(197812)42:6<2631::aid-cncr2820420619>3.0.co;2-i.
A study of some immunologic in vitro and in vivo changes during the course of chemotherapy in 17 cases of advanced Hodgkin's disease was made. Skin testing with PPD, candida albicans and streptodornase antigens was studied together with studies of B and T cell numbers in the blood and responses to migration inhibition testing for PPD and PHA. An excellent correlation was found between recovery of normal immunologic responses and clinical remission despite the use of immunosuppressive chemotherapy.
对17例晚期霍奇金病患者化疗过程中的一些体外和体内免疫变化进行了研究。研究了用结核菌素纯蛋白衍生物（PPD）、白色念珠菌和链道酶抗原进行的皮肤试验，同时研究了血液中B细胞和T细胞数量以及对PPD和PHA的迁移抑制试验的反应。尽管使用了免疫抑制化疗，但在正常免疫反应的恢复与临床缓解之间发现了极好的相关性。
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