儿童霍奇金病：T和B淋巴细胞的研究
Hodgkin's disease in children: investigation of T and B lymphocytes.
作者信息
Ilyin N V, Kolygin B A, Letsky V B, Fedoreev G A, Zubzhitsky Y N
出版信息
Neoplasma. 1978;25(1):75-81.
A study has been made of twenty-five untreated patients with Hodgkin's disease (H. D.), ageing from 3 to 13. We have analyzed the correlations of T and B lymphocytes of peripheral blood and the involved lymph nodes and also the functional peculiarities of T-cells in PHA-response. It is shown that as well as adults children with H. D. have the depression of T-system of immunity, more marked in the presence of general symptoms and biological stage "b". No significant influence of the clinical stage on the level of immunological disorders has been found.
对25例未经治疗的霍奇金病（H.D.）患儿（年龄3至13岁）进行了一项研究。我们分析了外周血及受累淋巴结中T淋巴细胞和B淋巴细胞的相关性，以及T细胞在PHA反应中的功能特性。结果表明，与成人一样，患霍奇金病的儿童也存在T免疫系统抑制，在有全身症状和生物学分期“b”时更为明显。未发现临床分期对免疫紊乱水平有显著影响。
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