Cobalt-catalyzed cyclization with the introduction of cyano, acyl and aminoalkyl groups.

An efficient synthesis of carbo- and heterocycles using C[double bond, length as m-dash]C, C[double bond, length as m-dash]O and C[double bond, length as m-dash]N bonds under cobalt catalysis is described. The substituents on olefins are key for controlling the regio- and chemoselectivity in the initial hydrogen atom transfer step and quaternary carbons are efficiently constructed under mild conditions. Cyclopropane cleavage and tandem cyclization give highly functionalized bicyclic skeletons in a single operation.