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青少年儿童前交叉韧带损伤后的膝关节病变:一项前瞻性病例系列研究,47 例患者平均随访 9.5 年。

Knee Pathology in Young Adults After Pediatric Anterior Cruciate Ligament Injury: A Prospective Case Series of 47 Patients With a Mean 9.5-Year Follow-up.

机构信息

Division of Orthopaedic Surgery, Oslo University Hospital, Oslo, Norway.

Oslo Sports Trauma Research Centre, Norwegian School of Sport Sciences, Oslo, Norway.

出版信息

Am J Sports Med. 2019 Jun;47(7):1557-1566. doi: 10.1177/0363546519837935. Epub 2019 Apr 29.

Abstract

BACKGROUND

The rate of secondary knee injuries after pediatric anterior cruciate ligament (ACL) injury is uncertain, and previous studies are limited because of poor methodology.

PURPOSE

To evaluate the incidence of new meniscal injuries since the initial diagnostic magnetic resonance imaging (MRI) of young adults who sustained a pediatric ACL injury. In addition, to evaluate meniscal and cartilage injuries in the index knee and contralateral knee injuries on MRI at final follow-up (9.5 years). Furthermore, to assess leg length and alignment based on long-leg radiographs.

STUDY DESIGN

Case series; Level of evidence, 4.

METHODS

Study population at final follow-up included 47 young adults who sustained a pediatric ACL injury before age 13 years. They were followed prospectively since the time of injury for a mean 9.5 years at final follow-up. Imaging included diagnostic MRI of the index knee and 3.0-T MRI of both knees at 1-, 2-, and 9.5-year follow-up, in addition to long-leg radiographs at final follow-up. Forty-three patients underwent active rehabilitation without ACL reconstruction initially; 4 were treated with initial ACL reconstruction. At final follow-up, 27 (57%) had undergone ACL reconstruction.

RESULTS

Fourteen patients had meniscal tears in the index knee at final follow-up (prevalence, 30%). The majority of these were in the same location as previously repaired tears (n = 9). Between diagnostic MRI and final follow-up, 16 patients had sustained new meniscal tears to a healthy meniscus (incidence, 34%). At final follow-up, meniscal injuries recorded at baseline or during follow-up were no longer visible and appeared healed in 17 patients (20 tears). MRI at final follow-up showed cartilage injuries in the index knee of 13 patients (28%) and contralateral injuries in 8 patients (meniscus, n = 2; cartilage, n = 5; subchondral fracture, n = 1). Two patients had a leg-length difference >15 mm, and 3 had side-to-side difference in knee alignment >5°.

CONCLUSION

The incidence of new meniscal tears after pediatric ACL injury was 34% during a mean follow-up period of 9.5 years. At final follow-up, 27 patients (57%) had normal menisci, and none had developed knee osteoarthritis. Primary active rehabilitation, close follow-up, and delayed surgery if needed may be a viable and safe treatment option for some pediatric ACL injuries.

摘要

背景

儿童前交叉韧带(ACL)损伤后二次膝关节损伤的发生率尚不确定,既往研究由于方法学较差而受到限制。

目的

评估青年人群中初次 ACL 损伤后发生新半月板损伤的发生率。另外,评估初次 ACL 损伤时的初始诊断磁共振成像(MRI)以及末次随访(9.5 年)时的指数膝关节和对侧膝关节的半月板和软骨损伤。进一步根据下肢全长 X 线片评估肢体长度和对线。

研究设计

病例系列;证据水平,4 级。

方法

末次随访时的研究人群包括 47 名 13 岁前发生 ACL 损伤的青年患者。他们自损伤时开始前瞻性随访,平均随访时间为 9.5 年。影像学检查包括初次 ACL 损伤时的指数膝关节 MRI 和 3.0-T 磁共振成像,以及初次 MRI 检查后的 1、2 和 9.5 年随访,末次随访时还进行下肢全长 X 线片检查。43 例患者最初未接受 ACL 重建,进行了积极的康复治疗;4 例患者接受了初次 ACL 重建。末次随访时,27 例(57%)患者接受了 ACL 重建。

结果

14 例患者在末次随访时出现了指数膝关节的半月板撕裂(患病率,30%)。其中大多数(n = 9)位于以前修复过的撕裂处同一位置。在初次 MRI 和末次随访之间,16 例患者发生了健康半月板的新半月板撕裂(发生率,34%)。在末次随访时,基线或随访过程中记录的半月板损伤在 17 例患者中已不可见,且已愈合(20 个撕裂)。末次随访时的 MRI 显示 13 例患者(28%)的指数膝关节存在软骨损伤,8 例患者(半月板,n = 2;软骨,n = 5;软骨下骨折,n = 1)对侧膝关节存在损伤。2 例患者存在 >15 mm 的肢体长度差异,3 例患者存在 >5°的膝关节对线差异。

结论

儿童 ACL 损伤后新半月板撕裂的发生率为 34%,平均随访时间为 9.5 年。末次随访时,27 例(57%)患者的半月板正常,无一例发展为膝关节骨关节炎。对于一些儿童 ACL 损伤,主动积极的康复治疗、密切随访和必要时延迟手术可能是一种可行且安全的治疗选择。

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