Cripps T P, Edmondson R S
Anaesthesia. 1987 Feb;42(2):189-91. doi: 10.1111/j.1365-2044.1987.tb02997.x.
A randomised single-blind trial was performed to compare the effects on cardiac rhythm of isoflurane and halothane in 100 dental outpatients having extractions under general anaesthesia in the dental chair without tracheal intubation. The incidence of supraventricular dysrhythmias did not differ significantly. No patient in the isoflurane group developed a ventricular dysrhythmia, whilst nine of those who received halothane did so (p = 0.0013). The quality of anaesthesia was acceptable in the isoflurane group, but induction time was longer (p less than 0.05) and the maximum heart rate was faster (p less than 0.01). There was no difference in the maximum end tidal carbon dioxide concentrations measured in a further 20 cases.
对100名在牙科椅上接受全身麻醉下拔牙且未行气管插管的牙科门诊患者进行了一项随机单盲试验，以比较异氟烷和氟烷对心律的影响。室上性心律失常的发生率无显著差异。异氟烷组无患者发生室性心律失常，而接受氟烷的患者中有9人发生了室性心律失常（p = 0.0013）。异氟烷组的麻醉质量可接受，但诱导时间较长（p < 0.05），最大心率较快（p < 0.01）。在另外20例患者中测得的最大呼气末二氧化碳浓度无差异。
