Departments of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University, Northwestern Medicine Multidisciplinary Eczema Center, Chicago, Illinois.
Ann Allergy Asthma Immunol. 2019 Aug;123(2):144-151. doi: 10.1016/j.anai.2019.04.020. Epub 2019 Apr 26.
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with substantial patient and population burdens. A number of comorbid health problems occur in patients with AD, aside from the cutaneous signs and symptoms. This review summarizes recent developments in the burden and comorbidities of AD.
Literature review.
Nonsystematic.
Different aspects of AD, such as chronic pruritus, psychosocial distress, and inflammation, can lead to anxiety, depression, or suicidality. Atopic dermatitis is associated with and may predispose to higher risk of other atopic disorders, including asthma, hay fever, food allergy, and eosinophilic esophagitis. Persons with AD appear to be at higher risk for infectious and cardiovascular risk.
Atopic dermatitis is associated with substantial burden and comorbidities. Identifying AD comorbidities is essential for proper disease management and improving overall patient outcomes.
特应性皮炎（AD）是一种慢性瘙痒性炎症性皮肤病，给患者和人群带来了巨大负担。除了皮肤症状和体征外，AD 患者还存在许多合并的健康问题。本综述总结了 AD 负担和合并症的最新进展。
文献回顾。
非系统性。
AD 的不同方面，如慢性瘙痒、心理社会困扰和炎症，可能导致焦虑、抑郁或自杀倾向。特应性皮炎与其他特应性疾病（包括哮喘、花粉症、食物过敏和嗜酸性食管炎）的风险增加有关，并且可能使这些疾病的风险增加。AD 患者似乎有更高的感染和心血管风险。
特应性皮炎与巨大的负担和合并症有关。识别 AD 的合并症对于适当的疾病管理和改善整体患者结局至关重要。
