Schemmer G B, Driebe W T
Arch Ophthalmol. 1987 Mar;105(3):342-4. doi: 10.1001/archopht.1987.01060030062026.
We encountered a patient who developed Bacillus cereus endophthalmitis following trauma. Early therapy, which included intravitreal clindamycin phosphate and gentamicin sulfate, resulted in a visual acuity of 20/60. A five-year retrospective review of all cases of endophthalmitis following trauma reported at our institution revealed Bacillus as the infecting organism in six (46%) of 13 culture-positive cases. The high frequency of virulent Bacillus infections in the setting of trauma necessitates the use of antibiotics that are active against this organism in posttraumatic endophthalmitis. The combination of clindamycin and gentamicin can be effective therapy in Bacillus species infections if used early in the course of the disease.
我们遇到一名患者,其在创伤后发生了蜡样芽孢杆菌性眼内炎。早期治疗包括玻璃体内注射磷酸克林霉素和硫酸庆大霉素,治疗后视力达到了20/60。对我院报告的所有创伤后眼内炎病例进行的一项为期五年的回顾性研究显示,在13例培养阳性病例中,有6例(46%)的感染病原体为芽孢杆菌。在创伤情况下,毒力强的芽孢杆菌感染频率较高,因此在创伤后眼内炎中必须使用对该病原体有效的抗生素。如果在疾病早期使用,克林霉素和庆大霉素联合使用可有效治疗芽孢杆菌属感染。