Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University Hospital, Baltimore, MD, USA.
Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, MI, USA.
Graefes Arch Clin Exp Ophthalmol. 2021 Sep;259(9):2473-2501. doi: 10.1007/s00417-020-04974-4. Epub 2020 Nov 6.
This review article is meant to serve as a reference guide and to assist the treating physician in making an appropriate selection and duration of an antimicrobial agent.
Literature review.
Infections of the posterior segment require prompt medical or surgical therapy to reduce the risk of permanent vision loss. While numerous options exist to treat these infections, doses and alternative therapies, especially with contraindications for first-line therapy, are often elusive. Antimicrobial agents to treat posterior segment infections can be administered via various routes, including topical, intravitreal, intravenous, and oral.
Although there are many excellent review articles on the management of endophthalmitis, we take the opportunity in this review to comprehensively summarize the appropriate antimicrobial regimen of both common and rare infectious etiologies of the posterior segment, using evidence from clinical trials and large case series.
本文旨在为临床医生提供参考，帮助其选择合适的抗菌药物并确定合适的疗程。
文献回顾。
后段感染需要及时进行医学或手术治疗，以降低永久性视力丧失的风险。尽管有许多治疗选择，但剂量和替代疗法，特别是对于一线治疗的禁忌证，往往难以确定。治疗后段感染的抗菌药物可通过多种途径给予，包括局部、玻璃体内、静脉内和口服。
尽管有许多关于眼内炎治疗的优秀综述文章，但我们在本文中利用临床试验和大型病例系列的证据，全面总结了常见和罕见后段感染病因的适当抗菌治疗方案。
