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减重手术后糖尿病与甲状腺功能减退的激素机制之间的关系。

Relationship Between Hormonal Mechanisms of Diabetes Mellitus and Hypothyroidism Post-Bariatric Surgery.

作者信息

Goes Lucas G, da Luz Eltchechem Camila, Wouk Jessica, Malfatti Carlos R M, da Silva Luiz A

机构信息

Department of Physical Education, Faculdade Guairaca, Guarapuava, Parana, Brazil.

Department of Physical Education, Universidade Estadual do Centro, Oeste, Brazil.

出版信息

Curr Diabetes Rev. 2020;16(3):200-203. doi: 10.2174/1573399815666190417145440.

Abstract

BACKGROUND

Obesity, diabetes mellitus may be related to the health, the relationship and the physiological capacity of the production of thyroid hormones (TH), triiodothyronine (T3) and thyroxine (T4).

OBJECTIVES

The main aims of this review are to describe the relationship between obesity, appetite, weight management, hormonal mechanisms of diabetes mellitus and hypothyroidism post-bariatric surgery.

METHODOLOGY

An in-depth literature search was conducted to identify scientific studies, which analyzed the correlation between diabetes mellitus and hypothyroidism post-bariatric surgery.

RESULTS

Bariatric surgery decreases hypothyroidism, reduces the need for pharmacological action (such as levothyroxine), controls the weight and body fat and increases the sensitivity to leptin and insulin.

CONCLUSION

The reduction of the stomach and intestine by bariatric surgery is an evolutionary and beneficial action, because it may lead to a drastic decrease on numbers of conditions such as diabetes, obesity, hypothyroidism, and others. Thus, new studies should also focus on patients' post-operatory conditions, such as lifetime, regulation and functioning of organs after reduced nutrition, and consumption and delivery of nutrients to health maintenance.

摘要

背景

肥胖、糖尿病可能与健康、甲状腺激素(TH)、三碘甲状腺原氨酸(T3)和甲状腺素(T4)产生的生理能力之间存在关联。

目的

本综述的主要目的是描述肥胖、食欲、体重管理、糖尿病的激素机制以及减肥手术后甲状腺功能减退之间的关系。

方法

进行了深入的文献检索,以确定分析减肥手术后糖尿病与甲状腺功能减退之间相关性的科学研究。

结果

减肥手术可降低甲状腺功能减退,减少药物治疗(如左甲状腺素)的需求,控制体重和体脂,并增加对瘦素和胰岛素的敏感性。

结论

减肥手术对胃和肠道的缩减是一种具有进化意义的有益行为,因为它可能会大幅减少糖尿病、肥胖、甲状腺功能减退等多种病症的发生。因此,新的研究也应关注患者的术后状况,如寿命、营养减少后器官的调节和功能,以及营养物质的消耗和输送对健康维持的影响。

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