Simas Luisa Amábile Wolpe, Zanatta Leila Caroline Bianchet, Moreira Carolina Aguiar, Borba Victoria Zeghbi Cochenski, Boguszewski Cesar Luiz
Serviço de Endocrinologia e Metabologia (SEMPR), Departamento de Medicina Interna , Universidade Federal do Paraná , Curitiba , PR , Brasil.
Arch Endocrinol Metab. 2019 May-Jun;63(3):265-271. doi: 10.20945/2359-3997000000121. Epub 2019 Apr 25.
We investigated changes in body composition and nutritional and metabolic parameters in a group of postmenopausal women who were classified as sufficient, insufficient and deficient in vitamin D.
A total of 106 postmenopausal women were included in this cross-sectional study and classified according to their serum levels of 25-OH-vitamin D as sufficient (≥ 30 ng/mL; group S), insufficient (20.1 and 29.9 ng/mL; group I) or deficient (≤ 20 ng/mL; group D) in vitamin D. Body composition was measured by dual-energy X-ray absorptiometry (DXA); dietary recall questionnaires were completed; and blood samples were analysed to compare the metabolic and nutritional status of the study groups.
Eleven (10.4%) of the women were classified in group S, 50 (47.2%) in group I and 45 (42.4%) in group D, with a mean serum level for 25-OH-D of 21.1 ± 7.0 ng/mL in all participants. Body composition did not differ among the groups. Serum levels of 25-OH-D were negatively correlated with serum levels of triglycerides, total cholesterol and LDL cholesterol.
Vitamin D insufficiency and deficiency were highly prevalent in our group of postmenopausal women, showing an association with an unfavourable lipid profile.
我们调查了一组绝经后女性的身体成分、营养和代谢参数的变化，这些女性被分类为维生素D充足、不足和缺乏。
本横断面研究共纳入106名绝经后女性，并根据她们血清25-羟基维生素D水平分类为维生素D充足（≥30 ng/mL；S组）、不足（20.1至29.9 ng/mL；I组）或缺乏（≤20 ng/mL；D组）。通过双能X线吸收法（DXA）测量身体成分；完成饮食回顾问卷；并分析血样以比较各研究组的代谢和营养状况。
11名（10.4%）女性被分类为S组，50名（47.2%）为I组，45名（42.4%）为D组，所有参与者的血清25-OH-D平均水平为21.1±7.0 ng/mL。各组之间的身体成分没有差异。血清25-OH-D水平与甘油三酯、总胆固醇和低密度脂蛋白胆固醇水平呈负相关。
在我们的绝经后女性组中，维生素D不足和缺乏非常普遍，显示出与不良血脂谱相关。
