Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Lupus. 2019 Jun;28(7):799-805. doi: 10.1177/0961203319846397. Epub 2019 May 1.
Cutaneous lupus erythematosus (CLE)-a common presentation of lupus erythematosus-may exist independently or as a part of the systemic manifestations of systemic lupus erythematosus. The effects of living with and treating a chronic condition such as CLE can be debilitating to a patient's health and finances. The management of patients with CLE is made particularly challenging by poor compliance, limited therapeutic options, scarcity of evidence supporting their use, and significant differences in costs of medications. Effective management of CLE should center on prevention, individualized treatment regimens, and a mutual understanding of the challenges that patients with CLE face. This article seeks to provide an overview of the efficacy, safety, and cost of therapeutic options for CLE.
盘状红斑狼疮（CLE）——红斑狼疮的常见表现——可能独立存在，也可能是系统性红斑狼疮全身表现的一部分。患有慢性疾病（如 CLE）并接受治疗会对患者的健康和经济状况产生严重影响。CLE 患者的依从性差、治疗选择有限、缺乏支持其使用的证据以及药物成本存在显著差异，这些因素使得 CLE 患者的管理极具挑战性。CLE 的有效管理应侧重于预防、个体化治疗方案以及对 CLE 患者所面临挑战的共同理解。本文旨在概述 CLE 的治疗选择的疗效、安全性和成本。
